Actively Recruiting

Phase Not Applicable
Age: 18Years - 45Years
FEMALE
ID06295250

ASHA Bangladesh: An Integrated Intervention Combining Depression Treatment and Poverty Alleviation for Low-Income Rural Women

Led by University of Massachusetts, Worcester · Updated on 2026-03-09

680

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

University of Massachusetts, Worcester

Lead Sponsor

I

International Centre for Diarrhoeal Disease Research, Bangladesh

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of combining poverty alleviation with depression treatment compared to depression treatment alone in low-income rural Bangladeshi women aged 18 to 45 who have depression. The study aims to find out if adding poverty alleviation improves depression symptoms at 6 months, reduces relapse at 18 months, and enhances treatment uptake and retention. Other outcomes include economic vulnerability, anxiety, culturally specific symptoms, quality of life, and function. The study includes a mixed methods evaluation examining how well the interventions are adopted and delivered. Participants are randomly assigned to one of two groups. The control group receives six sessions of a group-based psychotherapy adapted from the WHO Problem Management Plus program, focusing on problem solving, social support, behavioral activation, and relaxation. The experimental group receives the same psychotherapy plus a poverty alleviation package that includes financial literacy education, savings accounts, consumption support (equivalent to 1 kg of rice per day for six months), three goats with 12 months of feed and veterinary care, gardening supplies, and agricultural skill building. Participants in both groups take part in research interviews at 6, 12, and 18 months to assess depression and other outcomes. The study measures changes in depressive symptoms primarily at 6 months, with additional assessments of relapse, economic status, anxiety, function, quality of life, and tension over 18 months. A thorough implementation evaluation includes interviews with participants and staff to understand treatment adoption, retention, and fidelity. The total participation period spans 18 months.

CONDITIONS

Brief Title

ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression

Who Can Participate

Age: 18Years - 45Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 to 45 years
  • Low income or economic vulnerability as shown by household income of 15,000 Taka or less per month, food insufficiency in last six months, or land ownership of 10 decimals or less
  • Family willing to participate in the program
  • Ability to read a simple sentence
  • Depression score of 10 or higher on the PHQ-9 scale at the start
Not Eligible

You will not qualify if you...

  • Currently pregnant at screening
  • Cognitive or physical problems that prevent participation
  • Plans to move away or travel for more than one month during the 18-month study period
  • Household debt greater than 70,000 Taka

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 6 months

Participants receive a 6-session manualized group based psychotherapy treatment delivered by trained non professional peers. Those in the experimental group also participate in a poverty alleviation program including financial literacy education, savings accounts, consumption support, productive asset transfer, animal care, gardening supplies, and agricultural skill building.

6 group therapy sessions and 4 support group meetings over 6 months; 4 financial literacy sessions for experimental group

Follow-up

Duration - Up to 18 months

Participants are monitored for depressive symptoms, economic vulnerability, anxiety, function, quality of life, and tension through assessments after treatment ends.

Assessments at 6, 12, and 18 months

Trial Site Locations

Total: 1 location

1

International Centre for Diarrhoeal Disease Research

Dhaka, Dhaka Division, Bangladesh

Actively Recruiting

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Research Team

A

Alison Karasz, PhD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Published Research Related To This Trial

Prevalence and effects of mood disorders on work performance in a nationally representative sample of U.S. workers.

Ronald C Kessler, Hagop S Akiskal, Minnie Ames...

https://pubmed.ncbi.nlm.nih.gov/16946181