The economic burden of depression in the United States: how did it change between 1990 and 2000?
Paul E Greenberg, Ronald C Kessler, Howard G Birnbaum...
https://pubmed.ncbi.nlm.nih.gov/14728109Actively Recruiting
Led by University of Massachusetts, Worcester · Updated on 2026-03-09
680
Participants Needed
1
Research Sites
N/A
Total Duration
U
University of Massachusetts, Worcester
Lead Sponsor
I
International Centre for Diarrhoeal Disease Research, Bangladesh
Collaborating Sponsor
Researchers are evaluating the effects of combining poverty alleviation with depression treatment compared to depression treatment alone in low-income rural Bangladeshi women aged 18 to 45 who have depression. The study aims to find out if adding poverty alleviation improves depression symptoms at 6 months, reduces relapse at 18 months, and enhances treatment uptake and retention. Other outcomes include economic vulnerability, anxiety, culturally specific symptoms, quality of life, and function. The study includes a mixed methods evaluation examining how well the interventions are adopted and delivered. Participants are randomly assigned to one of two groups. The control group receives six sessions of a group-based psychotherapy adapted from the WHO Problem Management Plus program, focusing on problem solving, social support, behavioral activation, and relaxation. The experimental group receives the same psychotherapy plus a poverty alleviation package that includes financial literacy education, savings accounts, consumption support (equivalent to 1 kg of rice per day for six months), three goats with 12 months of feed and veterinary care, gardening supplies, and agricultural skill building. Participants in both groups take part in research interviews at 6, 12, and 18 months to assess depression and other outcomes. The study measures changes in depressive symptoms primarily at 6 months, with additional assessments of relapse, economic status, anxiety, function, quality of life, and tension over 18 months. A thorough implementation evaluation includes interviews with participants and staff to understand treatment adoption, retention, and fidelity. The total participation period spans 18 months.
CONDITIONS
ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression
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Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 months
Participants receive a 6-session manualized group based psychotherapy treatment delivered by trained non professional peers. Those in the experimental group also participate in a poverty alleviation program including financial literacy education, savings accounts, consumption support, productive asset transfer, animal care, gardening supplies, and agricultural skill building.
6 group therapy sessions and 4 support group meetings over 6 months; 4 financial literacy sessions for experimental group
Duration - Up to 18 months
Participants are monitored for depressive symptoms, economic vulnerability, anxiety, function, quality of life, and tension through assessments after treatment ends.
Assessments at 6, 12, and 18 months
Total: 1 location
1
International Centre for Diarrhoeal Disease Research
Dhaka, Dhaka Division, Bangladesh
Actively Recruiting
A
Alison Karasz, PhD
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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