Actively Recruiting
Study of Brain Development and Eating Behaviors in Children Ages 7 to 12 to Understand Obesity
Led by Johns Hopkins University · Updated on 2026-05-07
210
Participants Needed
4
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating why some children develop obesity by studying eating behaviors, genetic and environmental factors, and brain development. This project, RESONATE, extends a larger study called RESONANCE and focuses on children aged 7 to 12 years. The goal is to understand how early brain development and appetite-related behaviors contribute to obesity risk during middle childhood, a critical time for long-term metabolic health. The study involves a single group of participants who undergo various assessments including meal tests, behavioral tasks, and functional MRI scans. These tests measure food intake, responses to food-related cues, cognitive control, and brain activity related to appetite. Data collected will also include measures of weight and body fat to examine how brain function and behavior relate to obesity development. Participants will take part in tests such as eating from a buffet meal, snack intake when not hungry, and MRI tasks that observe brain responses to food and control stimuli. Researchers will track calorie consumption, body mass index, reward responses, and cognitive control during these activities. The study aims to link these findings with early-life risk factors to better understand obesity mechanisms, supporting the future creation of targeted preventive interventions.
CONDITIONS
Brief Title
Brain and Behavior Influences on Obesity Development From Infancy Through Childhood
Research Team
S
Susan Carnell, PhD
V
Viren D'Sa, MD
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