Actively Recruiting
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
Led by Mayo Clinic · Updated on 2025-12-30
147
Participants Needed
1
Research Sites
101 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological mechanisms are significant for patient populations facing complex health challenges, such as those with cancer and neurodegenerative disease, and their caregivers. By measuring oxygen delivery to brain tissues and cerebrospinal fluid flow, this trial may help researchers investigate the potential benefits of respiratory training for patients with MS and cancer and their caregivers.
CONDITIONS
Official Title
Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be physically fit enough to perform light exercise.
- Participants should read and understand English well enough to consent, complete measures, and follow instructions.
- Participants must have access to a smartphone or tablet.
- Cancer patients may have prostate cancer, neuroendocrine tumor, or brain cancer in any stage.
- The main focus is on pairs of cancer patients and their caregivers, but individual patients or caregivers can also join.
- Patients with multiple sclerosis are eligible for the MS study.
You will not qualify if you...
- Participants incompatible with MRI due to pacemakers or metallic implants.
- Those with chronic medical conditions like heart disease, chronic obstructive pulmonary disease, cystic fibrosis, cancer (other than study focus), diabetes, sleep apnea, aneurysms, epilepsy, Alzheimer's disease, Huntington's disease, essential tremor, or Parkinson disease are excluded.
- Participants with psychiatric conditions such as psychosis, suicidality, bipolar disorder, major depression, or substance use disorders.
- Caregivers for individuals with the above chronic conditions or cancer are excluded.
- Those with severe vision or hearing impairments.
- Individuals with a body mass index over 30.
- Pregnant individuals or those planning to become pregnant during the study period.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Mayo Clinic in Rochester
Rochester, Minnesota, United States, 55905
Actively Recruiting
Research Team
C
Clinical Trials Referral Office
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
7
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