Respiratory Training to Improve Brain and Mental Health in Adults with Cancer, Multiple Sclerosis, and Their Caregivers

What this Trial Is About

Researchers are evaluating the effects of respiratory training on brain and mental health in patients with multiple sclerosis MS, cancer, and their caregivers. This study focuses on understanding how breathing, cardiovascular functions in the brain, and mental well-being interact, especially for people facing complex health challenges. By measuring oxygen delivery to brain tissues and cerebrospinal fluid flow, the trial aims to explore potential benefits of respiratory training for these groups. Participants are assigned to one of three studies involving breathing exercises, walking routines, or both. Most participants engage in daily 30-minute breathing or walking self-practice routines via a mobile app for four months. Some may also join weekly online or monthly in-person breathing sessions. After four months, some groups continue their routines for an additional two months, while others discontinue. Throughout the study, participants undergo MRI scans, and MS patients also provide blood samples. During the trial, participants are monitored through questionnaires assessing mental health, fatigue, sleep quality, and caregiver strain. Researchers track adherence to breathing practices and measure changes in respiratory function alongside brain activity. The study spans up to six months, with ongoing assessments to evaluate long-term effects. The involvement includes regular self-practice, optional group sessions, MRI scans, and blood collections for MS patients.

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases