Actively Recruiting
Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)
Led by Roswell Park Cancer Institute · Updated on 2026-05-08
150
Participants Needed
1
Research Sites
N/A
Total Duration
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AI-Summary
What this Trial Is About
This research aims to evaluate the levels of nicotine, cannabis, and harmful toxicants in the blood and urine of young adults who use nicotine e-cigarettes and/or cannabis products. It focuses on understanding differences in self-reported use behaviors and exposure to carcinogens among different consumer groups. The study also gathers data to help plan future, larger studies by estimating effect sizes. Participants fall into one of three groups: those who mainly use nicotine e-cigarettes daily, those who primarily use cannabis at least three times per week, and those who co-use both daily e-cigarettes and cannabis multiple times per week. The study collects information through questionnaires and assessments about their use patterns and dependence. Participants choose their preferred location for study completion during scheduling. During a single study session lasting about one hour, participants provide samples and complete surveys assessing toxicant exposure, use behaviors, and psychosocial factors. Researchers measure biomarker differences between groups and record responses about recruitment methods and study interest. The study includes a follow-up period of up to one year to track participant engagement and recall of recruitment materials.
CONDITIONS
Brief Title
Carcinogen and Toxicant Exposure Among Young Adults Who Co-Use E-cigarettes and Cannabis (Co-Tox Study)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Young adults aged 18 to 25 years
- Able to read and write in English
- Predominant e-cigarette users: daily use of nicotine e-cigarettes for 6 months, minimal other nicotine or cannabis use
- Predominant cannabis users: cannabis use at least 3 times per week for 6 months, minimal nicotine or tobacco use
- Co-users: daily nicotine e-cigarette use and cannabis use at least 3 times per week for 6 months, minimal other nicotine product use
- No diagnosis of kidney disease currently or within the past year
- Willing to provide informed consent and understand study is voluntary
You will not qualify if you...
- Under 18 or over 25 years of age
- Currently pregnant or breastfeeding (for female participants)
- Unable or unwilling to follow study protocol requirements
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person or remote screening survey)
Duration - 1 hour
Participants complete assessments including self-reported measures of nicotine and cannabis use behaviors, psychosocial characteristics, and recall of recruitment materials. Biomarkers of exposure to toxicants and carcinogens are also collected during a study session.
1 study session (in-person)
Duration - Up to 1 year
Participants’ study interest and recall of recruitment methods are observed over up to 1 year following the initial assessment.
No scheduled visits; ongoing observation
Trial Site Locations
Total: 1 location
1
Roswell Park Comprehensive Cancer Center
Buffalo, New York, United States, 14263
Actively Recruiting
Research Team
A
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How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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