Actively Recruiting
Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
Led by National Institute of Mental Health (NIMH) · Updated on 2025-12-02
75
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating a new type of magnetic field sensor called an optically pumped magnetometer (OPM) for measuring magnetic fields produced by brain activity. This research aims to develop and test the OPM array and compare its performance to a standard MEG system. The study focuses on healthy adults aged 18 to 65 who previously had an MRI scan under a specific protocol. The study involves testing a 49-61 channel OPM MEG system and comparing it to a standard SQUID MEG system. Participants will complete sessions using both devices. During the sessions, sensors will be attached to the head—either via a cap for the OPM or coils taped to the face for the SQUID MEG. Participants will be seated in a magnetically shielded room and may complete various tasks involving visual, auditory, language, or somatosensory stimuli, including median nerve stimulation. Participation typically lasts one day, with optional additional scans over a year. Researchers will assess the OPM array's performance, including signal quality and spatial resolution, and evaluate the system's ability to map receptive fields of the fingers. Safety and participant cooperation are monitored throughout, with outcomes measured continuously during the study.
CONDITIONS
Brief Title
Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed and dated informed consent form
- Willingness to comply with all study procedures and availability for the study duration
- Male or female aged 18 to 65 years
- In good general health as evaluated under protocol 17-M-0181
- Completed a magnetic resonance imaging (MRI) scan under protocol 17-M-0181
You will not qualify if you...
- Exclusion from protocol 17-M-0181
- Presence of metal in the body that would cause artifacts on MEG recordings
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Duration of the protocol as scheduled
Participants undergo MEG recordings using both the investigational OPM MEG system and a standard SQUID MEG system with various stimuli to characterize the OPM array's performance.
1 to 2 visits depending on device testing
Trial Site Locations
Total: 1 location
1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892
Actively Recruiting
Research Team
A
Anna M Namyst
A
Allison C Nugent, Ph.D.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DEVICE_FEASIBILITY
Number of Arms
1
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