Development and Refinement of MRI and Spectroscopy Methods Using the 3T Philips Whole-Body Scanner for Aging Studies

What this Trial Is About

Researchers are conducting a study to develop and improve magnetic resonance imaging MRI and spectroscopy scanning methods using the new Philips 3T Achieva whole-body MRI scanner. This research focuses on both healthy adults and individuals with aging-related conditions to refine imaging techniques that will be useful for future clinical research in aging and related health topics. Participants will undergo MRI scans using the 3T scanner, which may include the injection of a small amount of radioactive contrast agent or radiotracer for some scans. Some participants might perform tasks involving thinking and movement during scanning to help test functional MRI procedures. The study does not provide treatment but focuses on trial scans and method development. Participants will complete a full medical history and physical examination, along with blood and urine tests before scanning. The study team will monitor the development of scanning procedures over about 2 months. Researchers aim to create noninvasive imaging markers for aging-related outcomes such as longevity, physical disability, cognitive function, and frailty. Participation involves a single MRI visit and related assessments.

Development of 3T Magnetic Resonance Research Methods for NIA Studies