Comparison of Closed and Open Chain Knee Exercises With Blood Flow Restriction for Adults With Knee Osteoarthritis

What this Trial Is About

This research investigates the effects of closed chain versus open chain exercises combined with blood flow restriction on pain, range of motion, strength, and functional performance in adults aged 45 to 75 with mild to moderate knee osteoarthritis. The study is a randomized controlled trial conducted at two medical centers with 40 participants divided equally between the two exercise groups. The trial aims to better understand which exercise approach may impact knee osteoarthritis symptoms and function. Participants receive either closed kinetic chain or open kinetic chain quadriceps strengthening exercises under blood flow restriction, alongside conservative therapy including hot packs, TENS, and Mulligan mobilization. Exercises follow a standardized low-load protocol with 4 sets of 30, 15, 15, and 15 repetitions performed three times weekly over four weeks, totaling 12 sessions. Each session lasts about 40 minutes and includes conventional physiotherapy elements. During the study, participants are assessed before and after the 4-week intervention using tools such as the Numeric Pain Rating Scale, Western Ontario and McMaster Universities Osteoarthritis Index WOMAC, goniometer measurements for knee flexion and extension, a dynamometer for muscle strength, and a 30-second chair stand test. Data analysis evaluates changes in pain, function, and strength. The study provides close monitoring throughout the 4-week treatment period to measure outcomes and safety.

Close Chain and Open Chain Exercises With Blood Flow Restriction in Knee Osteoarthritis