Actively Recruiting

Age: 18Years +
All Genders
ID07526831

Comparison of the Analgesic Efficacy of Adductor Canal Block Versus Adductor Canal Block Combined With Local Anesthetic Infiltration Between the Popliteal Artery and the Capsule of the Knee (IPACK) in Patients Undergoing Knee Surgery

Led by TC Erciyes University · Updated on 2026-05-14

60

Participants Needed

2

Research Sites

2 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effectiveness of two types of nerve blocks—Adductor Canal Block alone and Adductor Canal Block combined with the IPACK block—in reducing pain and the need for pain medicine after knee surgery, specifically total knee arthroplasty. This study aims to find out which method provides better postoperative pain relief using ultrasound-guided techniques. Participants are divided into two groups: one receives a single-shot Adductor Canal Block before surgery, and the other receives both the Adductor Canal Block and an IPACK block, also before surgery. Both groups will have access to a patient-controlled intravenous morphine device after surgery to manage pain. The study compares these two approaches to assess their impact on pain and opioid use. During the study, researchers will measure opioid consumption and pain scores at rest and during movement within the first 24 hours after surgery. They will also monitor side effects like nausea and vomiting during this period. Participants will be followed starting from the preoperative phase through at least 24 hours postoperatively to evaluate pain control and adverse effects.

CONDITIONS

Brief Title

Comparison of the Analgesic Efficacy of Adductor Canal Block and Combined Adductor Canal Block Plus IPACK Block in Knee Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients classified as ASA I, ASA II, or ASA III
Not Eligible

You will not qualify if you...

  • History of allergy to the study medication
  • Refusal to participate

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Day of surgery and immediate postoperative period

Participants receive either a preoperative adductor canal block alone or combined with an iPACK block under ultrasound guidance before knee surgery. Postoperative pain is managed with intravenous patient-controlled analgesia containing morphine.

1 preoperative visit and 1 postoperative visit (in-person)

Post-operative Follow-up

Duration - 24 hours after surgery

Participants are assessed for opioid consumption, pain scores, and adverse effects during the first 24 hours after surgery.

1 follow-up visit within 24 hours post-surgery

Trial Site Locations

Total: 2 locations

1

Sibel Pehlivan

Kayseri, Talas, Turkey (Türkiye), 38090

Actively Recruiting

2

Sibel Seckin Pehlivan

Kayseri, Turkey (Türkiye), 38039

Actively Recruiting

Loading map...

Research Team

S

Sibel Pehlivan, DR

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

Similar Trials

CR17-003 Truliant Knee PMCF: A Post-Market Domestic (US) and...

Knee Arthroplasty, Total

Actively Recruiting

5 locations

Infiltration of Local Anesthetics Between the Popliteal Arte...

Knee Arthroplasty, Total

Actively Recruiting

1 location

Computer-Assisted Surgery vs Standard Surgical Technique in ...

Knee Arthroplasty, Total

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

Combined Single-Shot Infiltration Between the Popliteal Artery and Capsule of the Knee and Adductor Canal Block With Bupivacaine, Dexmedetomidine, and Dexamethasone for Total Knee Arthroplasty: A Propensity-Matched Analysis.

Melina Shoni, Aneesh V Samineni, Seroos Salavati...

https://pubmed.ncbi.nlm.nih.gov/38235397

A randomized comparison of proximal and distal ultrasound-guided adductor canal catheter insertion sites for knee arthroplasty.

Edward R Mariano, T Edward Kim, Michael J Wagner...

https://pubmed.ncbi.nlm.nih.gov/25154949