Study Comparing Walking Ability After Total Knee Replacement Using Kinematic Versus Mechanical Alignment for Adults 55 to 80 Years with Knee Osteoarthritis

What this Trial Is About

Researchers are evaluating the walking patterns after total knee arthroplasty TKA in adults aged 55 to 80 with disabling femorotibial osteoarthritis. This study compares two types of knee replacements one that aligns the knee mechanically at 180 degrees and another that uses kinematic alignment to restore the patients original knee position. The goal is to understand how these approaches affect knee function and patient satisfaction, as about 20% of patients remain dissatisfied after TKA. The study involves randomly assigning participants to receive either a total knee arthroplasty with kinematic alignment or mechanical alignment. Both surgeries use a SPHERE prosthesis to replace the knee. The kinematic alignment group will have the prosthesis set to mimic their preoperative knee deformity, while the mechanical alignment group will have the prosthesis set to a standard 180-degree alignment. This approach aims to assess the impact of these surgical techniques on knee biomechanics. Participants will be monitored over time, with walking tests and knee function assessments conducted at 12 months and up to 60 months after surgery. Researchers will measure changes in walking speed, knee angles, knee motion, functional recovery, and patient ability to forget the prosthesis. Safety and complications will also be recorded. The study offers thorough follow-up to evaluate long-term outcomes of these knee replacement methods.

Evaluation of Walking Analysis After a Total Knee Arthroplasty With Kinematic Alignment Versus Mechanical Alignment