Actively Recruiting
Bacteria in Dental Plaque and Atheroma Plaque
Led by Istanbul Saglik Bilimleri University · Updated on 2025-08-03
60
Participants Needed
1
Research Sites
12 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to explore the connection between bacteria found in dental plaque and those in atheroma plaques in patients diagnosed with endarterectomy. The study focuses on understanding how oral bacteria and their by-products may travel through the bloodstream and contribute to conditions like atherosclerosis and systemic inflammation. The investigation also examines how demographic factors relate to bacterial presence and frequency in these tissues. Participants will have samples collected from atheroma plaques during their routine endarterectomy procedure. Additionally, dental plaque samples will be taken from beneath the gums prior to the procedure. This observational study classifies patients using the new periodontal classification to analyze the bacterial relationship in different groups. During the study, researchers will measure the number of bacteria in collected samples over an average of two months. Participants will undergo sample collection and monitoring without receiving experimental treatments. The study will assess bacterial counts and their potential impact, with overall participation lasting around two months from sample collection to study completion.
CONDITIONS
Brief Title
Bacteria in Dental Plaque and Atheroma Plaque
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosed with endarterectomy
- Not receiving chemotherapy
- Not having received this treatment before
You will not qualify if you...
- Having systemic infection
- Patients with severe heart disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Day of endarterectomy procedure
Participants provide dental plaque samples before their endarterectomy procedure and atheroma plaque samples are collected during the procedure.
1 visit (in-person)
Duration - Approximately 2 months
Participants are observed to assess the relationship between bacteria in atheroma and dental plaque over time.
Trial Site Locations
Total: 1 location
1
Health Sciences University, Hamidiye Faculty of Dentistry, Department of Periodontology
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
A
Ayşe Toraman
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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