COMPLEX Registry: Prospective Study on Management and Outcomes of Patients with Complex and Calcified Coronary Artery Disease

What this Trial Is About

Researchers are collecting detailed information about patients with complex and/or calcified chronic coronary artery disease (CAD) who have undergone percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG), as well as those managed medically. The study aims to compare clinical outcomes among these treatment groups and to understand how different PCI devices and CABG techniques affect cardiovascular health. It also examines patient subgroups such as those with diabetes or different ages and genders, evaluating their treatment differences and outcomes. The study observes patients receiving PCI, CABG, or medical management, gathering data on procedural results like blood flow and device performance in PCI, surgical details in CABG, and medical therapy regimens in conservatively managed patients. It analyzes short and long-term outcomes, including heart attacks, strokes, heart failure, bleeding, and death. The study also investigates predictors of treatment success or failure, economic aspects, and non-invasive testing methods. Participants provide baseline and clinical data and are followed over time to assess major adverse cardiac and cerebrovascular events (MACCE) up to 10 years after treatment. Researchers collect information on repeat procedures, hospitalizations, and complications through clinical evaluations. The study monitors safety and treatment effects continuously, aiming to improve understanding of how different management strategies impact patients with complex CAD.

COMPLEX Registry - a Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting with CompLEX and Calcified Coronary Artery Disease