Actively Recruiting
The Effects of Bariatric Surgeries on Glucose Metabolism
Led by The University of Texas Health Science Center at San Antonio · Updated on 2025-09-09
200
Participants Needed
2
Research Sites
630 weeks
Total Duration
On this page
Sponsors
T
The University of Texas Health Science Center at San Antonio
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is learn the effect of gastric bypass surgery and sleeve gastrectomy on glucose metabolism mediated by neural and hormonal factors initiated after eating.
CONDITIONS
Official Title
The Effects of Bariatric Surgeries on Glucose Metabolism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Hypoglycemic RYGB patients with documented blood glucose level <50 mg/dl
- Asymptomatic individuals with bariatric surgery
- Healthy non-surgical patients with no personal history of diabetes
- Subjects must physically be able to come to our clinical research center Cedars-Sinai Medical Center
You will not qualify if you...
- Active heart, lung, liver, gastrointestinal or kidney disease
- Unable to give informed consent
- Pregnancy
- Uncontrolled high blood pressure or high cholesterol
- Significant anemia (hemoglobin <11g/dL)
- Prisoners or institutionalized individuals
- Type 2 diabetes mellitus
- Development of any serious medical or psychiatric illness during recruitment or studies
- RYGB patients with gastric outlet obstruction or severe diarrhea
- Healthy non-surgical patients with personal history of diabetes
- History of glaucoma
- Uncontrolled hypertension (BP >140/90) and history of dyslipidemia
- Taking medications that might interact with atropine and cannot be stopped
- Myasthenia gravis
- Brain pathology
- Enlarged prostate in men
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Texas Diabetes Institute - University Health System
San Antonio, Texas, United States, 78207
Actively Recruiting
2
South Texas Veterans Health Care System
San Antonio, Texas, United States, 78229
Actively Recruiting
Research Team
M
Marzieh Salehi, MD MS
CONTACT
J
Jennifer Foster, MSN
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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