Actively Recruiting

Phase 2
Age: 21Years - 40Years
All Genders
Healthy Volunteers
NCT06446479

Effects of THC on Alcohol Consumption and Neural Correlates of Reward

Led by University of Colorado, Denver · Updated on 2024-08-19

28

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

Sponsors

U

University of Colorado, Denver

Lead Sponsor

N

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption patterns. The proposed study will explore the effects of oral THC (20mg dronabinol) vs. placebo on neural reward, alcohol self-administration and naturalistic co-use patterns.

CONDITIONS

Official Title

Effects of THC on Alcohol Consumption and Neural Correlates of Reward

Who Can Participate

Age: 21Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Drink alcohol
  • Use cannabis
  • Contact site for additional details
Not Eligible

You will not qualify if you...

  • MRI contraindications (implanted metal, weight > 315 lb, etc.)
  • Contact site for additional details

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Colorado Anschutz Medical Campus

Aurora, Colorado, United States, 80045

Actively Recruiting

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Research Team

E

Elnaz Nourollahimoghadam

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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Effects of THC on Alcohol Consumption and Neural Correlates of Reward | DecenTrialz