Actively Recruiting
Environmental Pollutants and Neurological Disorders: Clinical and Mechanistic Study
Led by Beijing Tiantan Hospital · Updated on 2025-08-24
500
Participants Needed
1
Research Sites
82 weeks
Total Duration
On this page
Sponsors
B
Beijing Tiantan Hospital
Lead Sponsor
C
Chinese Research Academy of Environmental Sciences
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research investigates the impact of environmental pollutants on neurological conditions, focusing on brain tumours and cerebrovascular diseases such as stroke and aneurysms. Scientists are studying how exposure to heavy metals, microplastics, PFAS, antibiotics, and endocrine-disrupting chemicals may affect brain health by crossing the blood-brain barrier and causing cellular changes. The study aims to fill gaps in understanding how these pollutants contribute to disease development and progression. Participants will have samples collected from multiple sources including blood, urine, hair, tumour, and surrounding tissues to profile pollutant exposure. This systematic approach will help explore molecular mechanisms linking pollutants to neurological diseases. The study is observational with no drug or treatment interventions, aiming to identify potential biomarkers for risk assessment and prevention. During the study, researchers will monitor participants over a period of up to 24 months to observe overall survival and disease progression. Additional assessments include neurological function measured by the modified Rankin Scale 90 days after sample collection. Participants' involvement will include consenting to sample collection and follow-up evaluations to help provide new insights into environment-brain interactions and disease outcomes.
CONDITIONS
Brief Title
Environmental Pollutants and Neurological Disorders
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Able to give informed consent to participate in the research
You will not qualify if you...
- Refusal to participate
- Pregnant or breastfeeding woman
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 24 months
Participants are observed over time to assess overall survival and progression of neurological disorders.
Periodic assessments during the 24-month period
Trial Site Locations
Total: 1 location
1
Beijing Tiantan Hospital
Beijing, Beijing Municipality, China, 100070
Actively Recruiting
Research Team
R
Runting Li, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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