Actively Recruiting
Analgesic Effect of Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block for Open Appendectomy Surgery
Led by Cairo University · Updated on 2026-03-17
68
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing the pain relief effects of two regional anesthesia techniques, the Erector Spinae Plane (ESP) block and the lateral Transversus Abdominis Plane (TAP) block, in adults undergoing open appendectomy surgery. This randomized controlled trial aims to evaluate which method better manages postoperative pain and reduces opioid use after surgery. Participants will receive either the ESP block at the T10 spinal level or the TAP block using a lateral approach after general anesthesia is induced. Both blocks involve injecting 20 mL of 0.25% bupivacaine guided by ultrasound. If pain control is insufficient during surgery, fentanyl boluses will be given. After surgery, patients will have scheduled paracetamol and diclofenac, with morphine doses provided if pain scores exceed 3 on the Numeric Rating Scale (NRS). During the study, researchers will measure total morphine use within the first 24 hours after surgery as the main outcome. Pain levels will be assessed at multiple time points up to 24 hours post-operation using the NRS. They will also evaluate recovery quality 24 hours after surgery. Participants will be closely monitored for pain control and side effects throughout the 24-hour postoperative period.
CONDITIONS
Brief Title
Erector Spinae Plane Block Versus Lateral Transversus Abdominis Plane Block for Open Abendectomy Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult patients undergoing open appendectomy surgery
You will not qualify if you...
- American Society of Anesthesiologists physical status greater than III
- Allergy to any study drugs
- Blood clotting disorders (coagulopathy)
- Local infection at injection site
- History of chronic pain or regular opioid use
- Inability to understand the Numeric Rating Scale (NRS)
- Pregnant or breastfeeding women
AI-Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Surgery day and 24 hours postoperative
Participants receive either the Erector Spinae Plane Block or the Transversus Abdominis Plane Block after induction of general anesthesia during open appendectomy surgery. Postoperative analgesia includes regular paracetamol and diclofenac, with morphine titration if pain persists.
1 surgery visit and multiple assessments within 24 hours postoperative
Trial Site Locations
Total: 1 location
1
Cairo University
Cairo, Cairo Governorate, Egypt
Actively Recruiting
Research Team
M
Maha Mostafa, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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