Actively Recruiting
Etiology and Treatment of Neonatal Seizure
Led by Children's Hospital of Fudan University · Updated on 2026-03-16
2000
Participants Needed
1
Research Sites
542 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Genetic diagnosis for neonates suffering from epilepsy has important implications for treatment, prognosis, and development of precision medicine strategies. Investigator performed exome sequencing (ES) or targeted sequencing on neonates with seizure onset within the first month of life. Investigator subgrouped our patients based on the onset age of seizure into neonatal and before 1 year (1-12 months), to compare the clinical and genetic features and treatment strategies.
CONDITIONS
Official Title
Etiology and Treatment of Neonatal Seizure
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Severe seizures in neonates or generalized epilepsy or intractable epilepsy in infancy with generalized tonic-clonic seizures
- Onset of seizures before 1 year of age
- Epileptic syndromes or epileptic encephalopathies with unknown cause
You will not qualify if you...
- History of trauma
- Central nervous system infections
- Hypoxic-ischemic encephalopathy
- Vascular events
- Systemic infections
- Diagnosed metabolic disorders
- Identified pathogenic copy-number variants by array-based comparative genomic hybridization (CGH)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children Hospital of Fudan University
Shanghai, Shanghai Municipality, China, 201102
Actively Recruiting
Research Team
W
Wenhao Zhou, Doctor
CONTACT
L
Lin Yang, Doctor
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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