Prospective Evaluation of New Techniques in Radiation Reduction for Cardiovascular Computed Tomographic Angiography

What this Trial Is About

Researchers are studying new methods of cardiac CT angiography that use lower doses of radiation to create images of the heart and blood vessels. This study aims to find out if these low-dose imaging techniques are accurate and if they can predict heart-related outcomes. It also monitors the progression of coronary artery disease and evaluates updated cardiac imaging software and artificial intelligence compared to standard imaging. Participants will undergo a CT scan of the heart and blood vessels using the Cannon Aquilion ONE CT system, which is designed to reduce radiation exposure. The scan may include a contrast agent to improve image quality and can last up to 2 hours. Additional imaging may be done based on initial results to assess disease progression or late events. Participants will be evaluated through physical exams, medical history, and blood tests to check kidney function. Follow-up may occur via phone or office visits to track any further cardiovascular testing or events. Researchers will compare cardiovascular events among participants with different levels of artery narrowing and assess the accuracy and quality of new imaging techniques. The study will continue until 2027 and includes safety monitoring and long-term outcome tracking.

Evaluating New Radiation Techniques for Cardiovascular Imaging