Actively Recruiting
Fluid Intake After Hemodialysis: Investigating the Relationship Between Time and Weight Gain During the Interdialytic Interval
Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2026-05-04
20
Participants Needed
2
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the relationship between fluid intake after hemodialysis and weight gain during the time between dialysis sessions in adults with chronic kidney disease who require maintenance hemodialysis. The study aims to better understand how thirst, driven by factors such as salt intake and fluid loss during dialysis, affects fluid accumulation, which can increase health risks. This observational research will focus on patients without diabetes or significant urine output to avoid bias from blood sugar and residual kidney function. Participants will monitor their body weight and blood pressure at home four times daily for one week between dialysis sessions using medical-grade scales and automated blood pressure devices. They will complete questionnaires about thirst, sodium intake, dry mouth, and recovery time after dialysis during the first visit. Some may collect urine volume on the last day before their next dialysis session. Daily reminder calls may be offered to help participants stay consistent with measurements. Throughout the study, participants will record changes in weight and blood pressure to analyze fluid gain patterns. Researchers will review primary outcomes like the time to reach half of the interdialytic weight gain and the cumulative percentage of weight gain over the week. Secondary outcomes include comparing weight gain curves at different times of day and correlating thirst with weight changes. Participants continue their usual medications and care during the study, which lasts about one week from the first to the next dialysis session.
CONDITIONS
Brief Title
Fluid Intake After Hemodialysis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Receiving thrice weekly maintenance hemodialysis
- Willing and able to provide written informed consent
You will not qualify if you...
- Diagnosis of diabetes mellitus
- Residual urinary volume greater than 500 ml per day
- Inability to self-monitor body weight and blood pressure
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 week
Participants will self-monitor their body weight and blood pressure at home four times a day for one week using provided medical grade scales and a validated blood pressure monitor. They will record measurements in a logbook and may receive daily reminder phone calls to support compliance.
Daily self-monitoring at home four times per day for 7 days
Trial Site Locations
Total: 2 locations
1
Adam Linton Unit
London, Ontario, Canada, N6A 5W9
Actively Recruiting
2
Westmount Kidney Care Centre
London, Ontario, Canada, N6K 1M6
Actively Recruiting
Research Team
C
Christopher W. McIntyre, MD, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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