Study of Fluid Intake and Weight Changes in Adults on Thrice Weekly Hemodialysis

What this Trial Is About

Researchers are studying the relationship between fluid intake after hemodialysis and weight gain during the time between dialysis sessions in adults with chronic kidney disease who require maintenance hemodialysis. The study aims to better understand how thirst, driven by factors such as salt intake and fluid loss during dialysis, affects fluid accumulation, which can increase health risks. This observational research will focus on patients without diabetes or significant urine output to avoid bias from blood sugar and residual kidney function. Participants will monitor their body weight and blood pressure at home four times daily for one week between dialysis sessions using medical-grade scales and automated blood pressure devices. They will complete questionnaires about thirst, sodium intake, dry mouth, and recovery time after dialysis during the first visit. Some may collect urine volume on the last day before their next dialysis session. Daily reminder calls may be offered to help participants stay consistent with measurements. Throughout the study, participants will record changes in weight and blood pressure to analyze fluid gain patterns. Researchers will review primary outcomes like the time to reach half of the interdialytic weight gain and the cumulative percentage of weight gain over the week. Secondary outcomes include comparing weight gain curves at different times of day and correlating thirst with weight changes. Participants continue their usual medications and care during the study, which lasts about one week from the first to the next dialysis session.

Fluid Intake After Hemodialysis