Actively Recruiting

Age: 18Years +
All Genders
ID04721652

Fluid Intake After Hemodialysis: Investigating the Relationship Between Time and Weight Gain During the Interdialytic Interval

Led by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · Updated on 2026-05-04

20

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying the relationship between fluid intake after hemodialysis and weight gain during the time between dialysis sessions in adults with chronic kidney disease who require maintenance hemodialysis. The study aims to better understand how thirst, driven by factors such as salt intake and fluid loss during dialysis, affects fluid accumulation, which can increase health risks. This observational research will focus on patients without diabetes or significant urine output to avoid bias from blood sugar and residual kidney function. Participants will monitor their body weight and blood pressure at home four times daily for one week between dialysis sessions using medical-grade scales and automated blood pressure devices. They will complete questionnaires about thirst, sodium intake, dry mouth, and recovery time after dialysis during the first visit. Some may collect urine volume on the last day before their next dialysis session. Daily reminder calls may be offered to help participants stay consistent with measurements. Throughout the study, participants will record changes in weight and blood pressure to analyze fluid gain patterns. Researchers will review primary outcomes like the time to reach half of the interdialytic weight gain and the cumulative percentage of weight gain over the week. Secondary outcomes include comparing weight gain curves at different times of day and correlating thirst with weight changes. Participants continue their usual medications and care during the study, which lasts about one week from the first to the next dialysis session.

CONDITIONS

Brief Title

Fluid Intake After Hemodialysis

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Receiving thrice weekly maintenance hemodialysis
  • Willing and able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Diagnosis of diabetes mellitus
  • Residual urinary volume greater than 500 ml per day
  • Inability to self-monitor body weight and blood pressure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - 1 week

Participants will self-monitor their body weight and blood pressure at home four times a day for one week using provided medical grade scales and a validated blood pressure monitor. They will record measurements in a logbook and may receive daily reminder phone calls to support compliance.

Daily self-monitoring at home four times per day for 7 days

Trial Site Locations

Total: 2 locations

1

Adam Linton Unit

London, Ontario, Canada, N6A 5W9

Actively Recruiting

2

Westmount Kidney Care Centre

London, Ontario, Canada, N6K 1M6

Actively Recruiting

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Research Team

C

Christopher W. McIntyre, MD, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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