Actively Recruiting
Food and Circadian Timing
Led by Oregon Health and Science University · Updated on 2025-11-10
14
Participants Needed
1
Research Sites
208 weeks
Total Duration
On this page
Sponsors
O
Oregon Health and Science University
Lead Sponsor
N
National Institutes of Health (NIH)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goals of this study are to uncover the influence of diet on the human circadian timing system. The protocol is a 46-day (28 outpatient days, 18 inpatient days over two 9 day visits) randomized cross-over study designed to elucidate the speed of entrainment in response to a high-fat diet.
CONDITIONS
Official Title
Food and Circadian Timing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy, lean men and women
- Between 18 and 40 years of age
You will not qualify if you...
- Major dietary restrictions such as entirely dairy-free or meat-free diets
- Body mass index (BMI) not between 18.5 and 24.9 kg/m2 or waist circumference exceeding 94 cm for men or 80 cm for women
- Psychiatric or psychological conditions unsuitable for participation
- Current use of drugs, alcohol, or smoking
- Use of prescribed or over-the-counter medications
- History of irregular day/night work, regular night work, or rotating shifts in the past year
- Travel across more than one time zone in the past three months
- Habitual consumption of a high-fat diet
- Chronobiologic or sleep disorders
- Cardiovascular diseases
- Metabolic syndrome, including any two of: low HDL cholesterol, high blood pressure, elevated fasting blood glucose, or high triglycerides
- Pre-diabetes or diabetes
- Hypertension
- Respiratory system disorders
- Kidney and urinary tract disorders
- Infectious diseases
- Gastrointestinal system disorders
- Immune system disorders
- Hematopoietic system disorders
- Neoplastic diseases
- Endocrine and metabolic diseases
- Neurologic disorders
- Current participation in another research study that affects safe participation
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Oregon Health & Science University
Portland, Oregon, United States, 97239
Actively Recruiting
Research Team
A
Andrew McHill, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
2
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