Actively Recruiting
Effect of Post Dinner Snack and Pre-Breakfast Consumption on Sleep Quality, Heart Rate Variability, Temperature, Interleukin-6, and Cortisol Levels in Healthy Males
Led by Riphah International University · Updated on 2024-08-14
80
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying how eating snacks after dinner and before breakfast affects sleep quality, heart rate variability (HRV), body temperature, and stress-related hormones like cortisol and interleukin-6 (IL-6) in healthy men aged 30 to 50. The study explores the body's natural 24-hour rhythm and how diet influences important health factors, including heart and mental health. This research aims to better understand how these snacks might impact the body's physiological processes and overall well-being. Participants are divided into groups receiving different combinations of snacks: some consume a post-dinner snack of nuts (including peanuts, walnuts, cashews, almonds, and pistachios) and various pre-breakfast snacks such as peanuts or raisins, while others receive no snacks. The study uses a randomized design with single masking, comparing these groups over an intervention period. Two assessments occur: one before and one after the intervention, with statistical analysis to compare the effects. During the study, participants will have their heart rate variability, sleep quality, cortisol and IL-6 levels, and body temperature measured at the start and after three weeks. Additional tests include blood pressure, heart rate, lipid profiles, liver and kidney function, inflammation markers, and stress scales. These evaluations help researchers monitor the participants' physiological responses and understand the impact of the dietary interventions on circadian rhythm and stress markers.
CONDITIONS
Brief Title
Impact of Evening Snacks and Pre-Breakfast Intake on Sleep, Heart Rate Variability, and Stress Markers in Healthy Males.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy males aged 30 to 50 years
- No comorbidities such as cardiovascular, neurological, respiratory, liver, or kidney diseases
- No skin allergies
You will not qualify if you...
- Individuals with any comorbidities including heart, liver, kidney, or respiratory diseases
- Individuals currently taking any medication
- Diagnosed insomnia
- Obesity with BMI greater than 30
- Smokers
- Diagnosed stress or anxiety
- Individuals with fever
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 3 weeks
Participants consume assigned post-dinner snacks and/or pre-breakfast supplements as per their group assignment to study the effects on sleep quality, heart rate variability, and stress markers.
1 baseline visit and 1 follow-up visit
Trial Site Locations
Total: 1 location
1
Imran Amjad
Islamabad, Punjab Province, Pakistan, 46000
Actively Recruiting
Research Team
H
Humaira Khan
S
Shazia Ali
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
BASIC_SCIENCE
Number of Arms
8
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