Actively Recruiting

Phase Not Applicable
Age: 18Years - 35Years
All Genders
Healthy Volunteers
ID07128862

Effects of Heavy-load Resistance Training With and Without Blood Flow Restriction Therapy on Quadriceps Muscle Strength and Endurance in Athletes

Led by Riphah International University · Updated on 2025-08-19

44

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of heavy-load resistance training (HLRT) with and without blood flow restriction (BFR) therapy on muscle strength and endurance in athletes aged 18 to 35. This single-blinded randomized controlled trial compares two training methods to understand how adding BFR influences muscle performance and physical activity levels in active individuals participating in sports regularly. Participants are divided into two groups: one performs HLRT combined with BFR and the other performs HLRT alone without BFR. Both groups follow the same exercise program involving back squats, leg press, and bench press at 70-80% of their one-repetition maximum (1RM), training three times per week for four weeks. BFR is applied using pneumatic cuffs inflated to 50% of limb occlusion pressure during working sets but deflated during rest periods. Training loads increase progressively based on participants' performance. During the study, participants undergo assessments at baseline and after four weeks measuring their 1RM strength for back squat and bench press, muscular endurance through a maximum repetition squat test and a one-minute push-up test, and physical activity levels via the International Physical Activity Questionnaire (IPAQ). The trial lasts about eight weeks and includes monitoring of exercise performance, adherence, and safety throughout the intervention period.

CONDITIONS

Brief Title

Heavy-load Resistance Training With and Without Blood Flow Restriction Therapy in Athletes

Who Can Participate

Age: 18Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Participants aged between 18 and 35 years
  • Active individuals participating in sports activities at least 3 times a week for the past 6 months
  • Participants without heart conditions
  • Individuals who voluntarily agree to participate and provide informed consent
  • Sprinters and football players
Not Eligible

You will not qualify if you...

  • Individuals with deep vein thrombosis (DVT) or other pulmonary artery diseases
  • Pregnant women or those planning to become pregnant
  • Participants with musculoskeletal injuries within the past 6 months
  • Individuals currently participating in another study
  • Participants allergic or sensitive to materials used in blood flow restriction bands
  • Individuals who expect they cannot attend all training sessions

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - 4 weeks

Participants engage in a 4-week heavy-load resistance training program, with or without blood flow restriction. Training includes back squats, leg press, and bench press exercises performed at 70-80% of their one-repetition maximum with progressive load increases based on performance.

Weekly visits for training sessions and assessments

Follow-up

Duration - 1 week

After completing the training program, participants undergo reassessment of muscle strength, endurance, and physical activity levels using standardized tests and questionnaires.

1 visit (in-person) for post-intervention data collection

Trial Site Locations

Total: 1 location

1

Pakistan Sports Board

Lahore, Punjab Province, Pakistan, 54000

Actively Recruiting

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Research Team

I

Imran Amjad, Phd PT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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