Actively Recruiting
Effects of Heavy-load Resistance Training With and Without Blood Flow Restriction Therapy on Quadriceps Muscle Strength and Endurance in Athletes
Led by Riphah International University · Updated on 2025-08-19
44
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of heavy-load resistance training (HLRT) with and without blood flow restriction (BFR) therapy on muscle strength and endurance in athletes aged 18 to 35. This single-blinded randomized controlled trial compares two training methods to understand how adding BFR influences muscle performance and physical activity levels in active individuals participating in sports regularly. Participants are divided into two groups: one performs HLRT combined with BFR and the other performs HLRT alone without BFR. Both groups follow the same exercise program involving back squats, leg press, and bench press at 70-80% of their one-repetition maximum (1RM), training three times per week for four weeks. BFR is applied using pneumatic cuffs inflated to 50% of limb occlusion pressure during working sets but deflated during rest periods. Training loads increase progressively based on participants' performance. During the study, participants undergo assessments at baseline and after four weeks measuring their 1RM strength for back squat and bench press, muscular endurance through a maximum repetition squat test and a one-minute push-up test, and physical activity levels via the International Physical Activity Questionnaire (IPAQ). The trial lasts about eight weeks and includes monitoring of exercise performance, adherence, and safety throughout the intervention period.
CONDITIONS
Brief Title
Heavy-load Resistance Training With and Without Blood Flow Restriction Therapy in Athletes
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants aged between 18 and 35 years
- Active individuals participating in sports activities at least 3 times a week for the past 6 months
- Participants without heart conditions
- Individuals who voluntarily agree to participate and provide informed consent
- Sprinters and football players
You will not qualify if you...
- Individuals with deep vein thrombosis (DVT) or other pulmonary artery diseases
- Pregnant women or those planning to become pregnant
- Participants with musculoskeletal injuries within the past 6 months
- Individuals currently participating in another study
- Participants allergic or sensitive to materials used in blood flow restriction bands
- Individuals who expect they cannot attend all training sessions
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 4 weeks
Participants engage in a 4-week heavy-load resistance training program, with or without blood flow restriction. Training includes back squats, leg press, and bench press exercises performed at 70-80% of their one-repetition maximum with progressive load increases based on performance.
Weekly visits for training sessions and assessments
Duration - 1 week
After completing the training program, participants undergo reassessment of muscle strength, endurance, and physical activity levels using standardized tests and questionnaires.
1 visit (in-person) for post-intervention data collection
Trial Site Locations
Total: 1 location
1
Pakistan Sports Board
Lahore, Punjab Province, Pakistan, 54000
Actively Recruiting
Research Team
I
Imran Amjad, Phd PT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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