Actively Recruiting
Impact of a 24-hour Shift Call on the Immune Status of Surgery Residents
Led by University of Chicago · Updated on 2025-12-09
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Sleep deprivation is a common issue that can cause hormonal changes and increase inflammation. This research focuses on surgery residents who undergo 24-hour shifts, exploring how such sleep deprivation may affect their immune system by studying immune cell types and functions along with biometric data. The study aims to better understand immune response changes during prolonged work hours. Participants include General Surgery residents working 24-hour rotation shifts. The study involves blood sample collection to examine immune cells before and after a 24-hour shift and after a month on call. Participants will also wear an Actigraph GT9X-BT device daily for a week to monitor steps, sleep, and heart rate, which will be collected at the end of the study. During the study, participants will undergo blood tests and biometric monitoring. Researchers will analyze immune cell characteristics through flow cytometry within 24 hours and compare these with biometric data such as sleep and physical activity recorded before and after rotations. The study monitors immune function and physical data over the course of a month, providing insights into how extended shifts impact immune health.
CONDITIONS
Brief Title
Immune Status After Being on Call for 24 Hrs
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy subjects
- Surgery residents in a 24-hour shift rotation
- Males and females
- 18 years old and older
- Any race or ethnicity
You will not qualify if you...
- Unwilling or unable to sign informed consent
- Vulnerable subjects or unable to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 month
Participants provide blood samples to characterize the phenotype and function of immune cells before and after a 24-hour shift and after a month of being on call.
5 visits including blood sample collections and monitor returns
Duration - 2 weeks
Participants wear an actigraph monitor daily for one week before rotation and during the last week of rotation to collect step count, sleep, and heart rate data.
Daily use of the actigraph monitor for 14 days
Trial Site Locations
Total: 1 location
1
The University of Chicago
Chicago, Illinois, United States, 60637
Actively Recruiting
Research Team
A
Angelica Perez-Gutierrez, MD
L
Leila Yazdanbakhsh
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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