Actively Recruiting
Immune Status After Being on Call for 24 Hrs
Led by University of Chicago · Updated on 2025-12-09
60
Participants Needed
1
Research Sites
162 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Sleep deprivation is a prevalent problem in modern societies. Sleep deprivation can cause hormonal changes, such as an increase in cortisol, as well as inflammation. Animal studies have shown an increase in inflammatory cytokine production following sleep deprivation. Additionally, humans experiencing sleep deprivation may experience a decrease in natural killer cells and lymphocytes. Physicians, particularly those in surgical specialties, are often subjected to sleep deprivation as part of their medical residency training. This study hypothesizes that after 24-hour shifts, there is an increase in inflammatory response and impairment of the immune response against unspecific activation. This proposal aims to provide insight into the impact of sleep deprivation on the immune system of surgery residents by characterizing the phenotype and function of immune cells, as well as their correlation with biometric data.
CONDITIONS
Official Title
Immune Status After Being on Call for 24 Hrs
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Healthy subjects
- Surgery residents in a 24-hour shift rotation
- Male or female gender
- Age 18 years and older
- Any race or ethnicity
You will not qualify if you...
- Unable or unwilling to sign informed consent
- Vulnerable subjects or unable to provide consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The University of Chicago
Chicago, Illinois, United States, 60637
Actively Recruiting
Research Team
A
Angelica Perez-Gutierrez, MD
CONTACT
L
Leila Yazdanbakhsh
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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