Prospective Registry and Biobank of Patients With Infectious Diseases
Led by IRCCS San Raffaele · Updated on 2026-04-20
10000
Participants Needed
1
Research Sites
26 weeks
Total Duration
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What this Trial Is About
Researchers are collecting information about patients with various infectious diseases to create a detailed database and biobank. This observational study focuses on illnesses such as bloodstream infections, central nervous system infections, bone and joint infections, endovascular infections, sexually transmitted infections, HIV infection, and emerging infectious diseases. The goal is to understand the clinical, laboratory, imaging, and microbiological features as well as treatment approaches, and to study factors affecting treatment success and disease outcomes.
Participants will provide biological samples like blood, cerebrospinal fluid, and urine at the start of their infectious disease diagnosis. Data and samples will be collected at baseline, end of treatment, and six months later, or yearly for HIV patients. Additional collections may occur depending on disease progression or treatment changes. The study will record clinical scores, laboratory results, imaging, treatment details, drug levels, and outcomes including mortality and complications.
Participants will be monitored through clinical and laboratory assessments at several time points including baseline, end of treatment, and follow-up visits. Researchers will use these data to analyze disease characteristics, treatment responses, and outcomes over time. The study aims to identify biomarkers, predictors of cure, and factors influencing mortality and complications. Participation involves donating samples and sharing medical information, with follow-up lasting at least six months or longer for some conditions.
CONDITIONS
Brief Title
INfectious DIsease REgistry BIObank
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
Patients with clinically suspected or microbiologically documented infectious diseases (bacterial, viral, fungal or parasitic)
At least 18 years of age or older
Able to provide informed consent
Participants unable to give consent must have a legal representative
You will not qualify if you...
Participants unable to understand the study protocol or give informed consent and who have no legal representative
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Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Monitoring
Duration - Up to 6 months after the end of treatment or 6 months after diagnosis if no treatment is given; yearly follow-up for participants with HIV infection
Participants who undergo routine care for infectious diseases are observed. Data and biological samples are collected at baseline and during follow-up to assess clinical, microbiological, and treatment characteristics of their condition.
Baseline visit, end of treatment visit, 6-month follow-up visit; yearly visits for participants with HIV infection
The INfectious DIsease REgistry BIObank (INDI-REBIO): protocol for the design and implementation of a single-centre, prospective registry and biobank in a tertiary care centre in Italy for advancing infectious disease research.