Actively Recruiting
The Effect of Low-Flow Anesthesia on Hemodynamics in Open-Heart Surgery
Led by Çağrı Özdemir · Updated on 2026-05-27
80
Participants Needed
1
Research Sites
3 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the effects of low-flow anesthesia (LFA) at different fresh gas flow rates on hemodynamic parameters during open-heart surgery. The study aims to understand if varying these flow rates influence heart rate, blood pressure, oxygen saturation, and anesthesia monitoring values during surgery. This observational study focuses on patients undergoing open-heart surgery and evaluates key physiological and monitoring parameters to guide anesthesia practices. Participants are divided into four groups based on anesthesia monitoring techniques and fresh gas flow rates. All groups receive 4% Sevoflurane, with fresh gas flows set at either 0.5 L/min or 1 L/min. Groups are monitored either by Bispectral Index (BIS) or Minimum Alveolar Concentration (MAC) methods. This setup allows comparison of hemodynamic outcomes under different anesthesia flow and monitoring conditions during the surgical procedure. During the study, researchers will collect intraoperative data including heart rate, blood pressure, oxygen saturation, BIS, and MAC values. Preoperative assessment data such as ASA classification and other baseline measurements will be gathered 24 hours before surgery. Participation involves monitoring and data collection during surgery, with careful observation of physiological parameters to evaluate the impact of anesthesia flow rates on patient hemodynamics.
CONDITIONS
Brief Title
Low-Flow Anesthesia and Open-Heart Surgery
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years and older scheduled for open-heart surgery
- ASA physical status class I, II, III, or IV
You will not qualify if you...
- Emergency cases
- Under 18 years of age
- Previous open-heart surgery
- Contraindication to inhaled anesthetic agents
- Not signing voluntary consent form
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo preoperative assessments and data collection 24 hours before surgery.
1 visit (in-person) 24 hours before surgery
Duration - Day of surgery
Participants receive open-heart surgery under low-flow anesthesia with monitoring during the procedure.
1 surgical visit (in-person)
Duration - Short-term post-surgery period
Participants are observed after surgery to monitor physiological parameters and recovery.
Visits as part of routine post-operative care
Trial Site Locations
Total: 1 location
1
Gazi University Faculty of Medicine
Ankara, Turkey (Türkiye)
Actively Recruiting
Research Team
Ç
Çağrı Özdemir
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here