Actively Recruiting
Studying How Low-Flow Anesthesia Affects Heart Function During Open-Heart Surgery
Led by Çağrı Özdemir · Updated on 2026-05-27
80
Participants Needed
1
Research Sites
3 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the effects of low-flow anesthesia LFA at different fresh gas flow rates on hemodynamic parameters during open-heart surgery. The study aims to understand if varying these flow rates influence heart rate, blood pressure, oxygen saturation, and anesthesia monitoring values during surgery. This observational study focuses on patients undergoing open-heart surgery and evaluates key physiological and monitoring parameters to guide anesthesia practices. Participants are divided into four groups based on anesthesia monitoring techniques and fresh gas flow rates. All groups receive 4% Sevoflurane, with fresh gas flows set at either 0.5 Lmin or 1 Lmin. Groups are monitored either by Bispectral Index BIS or Minimum Alveolar Concentration MAC methods. This setup allows comparison of hemodynamic outcomes under different anesthesia flow and monitoring conditions during the surgical procedure. During the study, researchers will collect intraoperative data including heart rate, blood pressure, oxygen saturation, BIS, and MAC values. Preoperative assessment data such as ASA classification and other baseline measurements will be gathered 24 hours before surgery. Participation involves monitoring and data collection during surgery, with careful observation of physiological parameters to evaluate the impact of anesthesia flow rates on patient hemodynamics.
CONDITIONS
Brief Title
Low-Flow Anesthesia and Open-Heart Surgery
Research Team
Ç
Çağrı Özdemir
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here