Actively Recruiting
MS-ResearchBiomarkerS
Led by Cedars-Sinai Medical Center · Updated on 2024-02-06
1000
Participants Needed
1
Research Sites
1043 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study is being conducted to investigate risk factors for disability progression in Multiple Sclerosis and related disorders (MSRD). The primary goal is to assess whether combining information from visual assessment, blood markers, as well as historical and ongoing longitudinal MRIs of the brain, orbit (the part of the skull where eyes are located), and/or spinal cord can predict changes in quantitative disability measures related to MSRD and neurological disease.
CONDITIONS
Official Title
MS-ResearchBiomarkerS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of MS, CIS, or RIS based on the 2017 revised McDonald criteria
- Diagnosis of NMOSD based on the 2015 revised NMOSD consensus diagnostic criteria
- Diagnosis of MOG-related encephalomyelitis, optic neuritis, or related disease
- Diagnosis of other neurological disorders besides MSRD
- Healthy volunteer
- Age 18 years or older
- Able to give informed consent
You will not qualify if you...
- Contraindication to MRI such as metallic implants, foreign bodies, claustrophobia, or incompatible pacemakers or heart valves
- Pregnancy (excluded only from MRI portions; other data may still be collected)
- Recent ocular surgery within past two months
- Refractive errors of ±6 diopters or greater
- Eye diseases that may affect or confuse OCT/OCTA measurements, including macular degeneration, advanced geographic atrophy, diabetic retinopathy, or glaucoma
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Cedars-Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
Research Team
O
Omar Al-Louzi, MD
CONTACT
G
Group Neurology Research
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
5
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