Actively Recruiting

Age: 18Years +
All Genders
NCT06476678

Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions

Led by Baylor College of Medicine · Updated on 2026-03-25

50

Participants Needed

1

Research Sites

167 weeks

Total Duration

On this page

Sponsors

B

Baylor College of Medicine

Lead Sponsor

C

Creo Medical Limited

Collaborating Sponsor

AI-Summary

What this Trial Is About

Both Baylor St Luke's Medical Center and Mayo Scottsdale are considered endoscopic submucosal dissection (ESD) centers of excellence. The investigators at Baylor College of Medicine have previously reported our Esophageal ESD experience using the monopolar current knife. Moreover, the research team have previously reported on the clinical efficacy of the bipolar RFA knife during per-oral endoscopic myotomy (POEM) and colonic ESD. The goal of our study is to prospectively evaluate the efficacy, safety and feasibility of Esophageal ESD using a novel Bipolar-Current ESD device.

CONDITIONS

Official Title

Novel Bipolar Radiofrequency Ablation Knife in Esophageal Lesions

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient is >18 years of age
  • Patient can provide informed consent
  • Patient is referred for resection of precancerous lesions that are mucosal based polyps
  • Lesions are located at the gastroesophageal junction (GEJ) or proximal to GEJ
  • No previous endoscopic resection attempted (EMR or ESD)
Not Eligible

You will not qualify if you...

  • Patients with International Normalized Ratio (INR) >1.5 or Platelets <50,000
  • Lesions extending past gastroesophageal junction (GEJ)
  • Subepithelial lesions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Baylor College of Medicine

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

S

Salmaan A Jawaid, MD

CONTACT

H

Haydee Rochits Cueto

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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