Actively Recruiting
Ozone Application Before Fissure Sealants
Led by IRCCS Burlo Garofolo · Updated on 2025-05-16
67
Participants Needed
1
Research Sites
393 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Decay is a multifactorial infective degenerative disease of hard dental tissues, caused by Streptococcus mutans and Lactobacillus forming the bacterial biofilm of teeth surfaces. Decays generally evolve in fissures and pits of secondary molars. Pits and fissure sealants prevent decays if performed in two years from eruption. Ozone has bactericidal effect and remineralizing capacity on enamel. The aim of this study is to assess the effectiveness of ozone application before sealants in increasing their duration in time.
CONDITIONS
Official Title
Ozone Application Before Fissure Sealants
Who Can Participate
Eligibility Criteria
You may qualify if you...
- First or second secondary molars to be sealed
- Ability to isolate both teeth involved with a rubber dam
- No clear signs of pigmentations on the teeth
- Good general health
You will not qualify if you...
- Allergy to latex
- Epilepsy or other severe neurological disorders
- Psychiatric disease
- Excessive sensitivity to electrical current
- Severe asthma
- Enamel disorders such as amelogenesis imperfecta, white spots, fluorosis, or Molar Incisors Hypomineralization
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Institute for Maternal and Child Health - IRCCS Burlo Garofolo-
Trieste, Trieste, Italy, 34137
Actively Recruiting
Research Team
M
Milena Cadenaro, DDS,MSc,PhD
CONTACT
C
Chiara Navarra, DDS,MSc,PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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