Actively Recruiting

Phase 4
Age: 65Years +
All Genders
NCT05640453

Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting

Led by Tanta University · Updated on 2025-06-25

70

Participants Needed

1

Research Sites

178 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this study is to determine the effect of pregabalin versus dexmedetomidine on the treatment and lasting duration of delirium in fast tracking elderly patients after Coronary Artery Bypass Grafting.

CONDITIONS

Official Title

Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting

Who Can Participate

Age: 65Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 65 years or older undergoing Coronary Artery Bypass Grafting (CABG)
  • Both genders eligible
  • American Society of Anesthesiologists (ASA) physical status classification II or III
  • Planned for fast track development of postoperative delirium (POD)
Not Eligible

You will not qualify if you...

  • History of psychiatric diseases or inability to communicate
  • Previous episodes of postoperative delirium
  • Preoperative sick sinus syndrome
  • Allergy or sensitivity to pregabalin or dexmedetomidine
  • Severe bradycardia (heart rate less than 50 beats per minute)
  • Second-degree or higher atrioventricular block without a pacemaker
  • Severe hepatic or renal insufficiency
  • Previous cardiac or thoracic surgery
  • Known diagnosis of depression or other major psychiatric diseases
  • Cognitive impairment or inability to cooperate with the study
  • History of substance abuse

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Islam Morsy

Tanta, El-Gharbia Governorate, Egypt

Actively Recruiting

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Research Team

I

Islam Morsy, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Pregabalin Versus Dexmedetomidine for Delirium Treatment After Coronary Artery Bypass Grafting | DecenTrialz