Actively Recruiting

Age: 18Years - 65Years
FEMALE
ID06777134

Relationship Between Pelvic Floor Dysfunctions and Core Endurance, Hip Rotation Muscle Strength, Tibialis Anterior and Tibialis Posterior Muscle Activation in Patients With Multiple Sclerosis

Led by Berivan Beril Kılıç · Updated on 2026-02-20

73

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating how pelvic floor dysfunctions relate to core endurance, hip external rotation muscle strength, and the activation of tibialis posterior and tibialis anterior muscles in people diagnosed with multiple sclerosis (MS). The study aims to understand these muscle functions and their connections to pelvic floor health in MS patients. Participants will undergo several assessments including the Pelvic Floor Distress Inventory-20 to evaluate pelvic floor dysfunction severity, the Multiple Sclerosis International Quality of Life Questionnaire, and McGill's core endurance tests measuring trunk flexor, extensor, and lateral flexor endurance. Hip adductor and external rotator muscle strength will be measured using a handheld dynamometer. Muscle activation of the tibialis posterior and anterior will be assessed using surface electromyography with the NeuroTrac Myoplus Pro device. During the study, participants will complete muscle strength and activation tests, core endurance holds, and quality of life questionnaires. Researchers will collect baseline data on pelvic floor muscle dysfunction and secondary measures including quality of life, core endurance, hip strength, and detailed muscle activation parameters. The study will monitor these outcomes to explore the relationships between muscle function and pelvic floor health in MS patients aged 18 to 65 years.

CONDITIONS

Brief Title

Relationship Between Pelvic Floor Dysfunctions and Lower Limb Strength and Activation in MS Patients

Who Can Participate

Age: 18Years - 65Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • EDSS score between 0 and 4.0
  • Access to the internet via a high-speed smartphone or computer
  • Scoring at least 21 points on the MoCA
  • Having a score of Stage 3 or higher on the Functional Ambulation Scale
  • Female aged between 18 and 65 years
  • Diagnosis of multiple sclerosis
Not Eligible

You will not qualify if you...

  • Having hearing or vision problems
  • Participating in any exercise program
  • Having other neurological, cardiovascular, or orthopedic disorders
  • History of MS relapse or medication change within the last 6 months
  • Physical condition preventing participation in exercises
  • Comorbid conditions negatively affecting oxygen transport (e.g., severe anemia, peripheral artery disease)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - 1 day

Participants undergo assessments to evaluate pelvic floor dysfunction, core endurance, hip strength, and muscle activation of the tibialis anterior and posterior muscles using questionnaires and EMG devices.

1 visit (in-person)

Long-term Monitoring

Duration - Up to study completion

Participants are observed over time without intervention to monitor the relationship between pelvic floor dysfunction and lower limb strength and activation.

Follow-up assessments may be done depending on study schedule

Trial Site Locations

Total: 1 location

1

Biruni University

Istanbul, Istanbul, Turkey (Türkiye), 34103

Actively Recruiting

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Research Team

B

BERİL KILIÇ, Asst. Prof.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Tibialis posterior in health and disease: a review of structure and function with specific reference to electromyographic studies.

Ruth Semple, George S Murley, James Woodburn...

https://pubmed.ncbi.nlm.nih.gov/19691828

Needle EMG registration of striated urethral wall and pelvic floor muscle activity patterns during cough, Valsalva, abdominal, hip adductor, and gluteal muscle contractions in nulliparous healthy females.

K Bø, R Stien

https://pubmed.ncbi.nlm.nih.gov/8156073

Strengths of pelvic floor muscles in women with multiple sclerosis and its relationship with urinary incontinence and quality of life.

Poorandokht Afshari, Parvin Abedi, Nastaran Majdinasab...

https://pubmed.ncbi.nlm.nih.gov/39871990