Actively Recruiting

Age: 18Years - 75Years
All Genders
NCT05793203

Single-center Prospective Study of Non-invasive Methods for the Diagnosis of Postoperative Complications in Liver Transplant Recipients

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2023-03-31

100

Participants Needed

1

Research Sites

390 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

A lot of different early and late complications may occur after liver transplantation. They could be related to surgical procedure, to infectious diseases or immuno-mediated diseases (acute cellular rejection, ACR). Almost all of those complications are characterized by an elevation in liver enzymes (ALT, AST and GGT) and a decline of liver function tests (serum bilirubin and INR increase) possibly leading to early allograft disfunction (EAD). In this scenario there is a lack of biomarker that could predict the development of ACR and/or EAD. The aim of this study is to explore the prognostic role of non-invasive instrumental and biological marker in the early post-transplant phase.

CONDITIONS

Official Title

Single-center Prospective Study of Non-invasive Methods for the Diagnosis of Postoperative Complications in Liver Transplant Recipients

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients eligible for liver transplantation following National and International Guidelines
Not Eligible

You will not qualify if you...

  • Unable or unwilling to give informed consent
  • Patients who have had a previous liver transplant
  • Liver transplant due to fulminant hepatitis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fondazione Policlinico Universitario A. Gemelli IRCCS

Rome, Italy, 00181

Actively Recruiting

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Research Team

L

Luca Miele, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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