Actively Recruiting

Phase Not Applicable
Age: 60Years - 75Years
All Genders
Healthy Volunteers
NCT05296980

Validation of the REMINDER Dementia Risk Reduction Program

Led by University of Coimbra · Updated on 2024-05-08

400

Participants Needed

1

Research Sites

234 weeks

Total Duration

On this page

Sponsors

U

University of Coimbra

Lead Sponsor

F

Fundação para a Ciência e a Tecnologia

Collaborating Sponsor

AI-Summary

What this Trial Is About

Until now, neuropsychological interventions aimed to optimize cognitive function and to have functional impact in individuals at risk of AD (MCI patients) were scarce in validity studies. While some RCTs have been developed in cognitive training interventions, comparative studies of merged interventions (cognitive, social and behavioral stimulation) with adequate control groups are absent, diminishing the professionals' trust on the adoption of these interventions for supporting patients. As such, the present proposal will develop a validation trial testing a multicomponent neuropsychological intervention (REMINDER), based on personal development, cognitive compensatory aids, meaningful goals setting, and behavior change techniques. The investigators will analyze its short/long-term gains and AD conversion rates. By aiming to provide a good validation study for REMINDER, the investigators will examine neurobiological, neurocognitive and functional outcomes of this intervention in comparison with an active control group (psychoeducation) in order to foster an effective outcome assessment of an intervention for individuals at risk of AD.

CONDITIONS

Official Title

Validation of the REMINDER Dementia Risk Reduction Program

Who Can Participate

Age: 60Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 60 or older
  • CAIDE dementia risk score greater than 8
  • No significant cognitive impairment according to Addenbrooke's Cognitive Examination-REVISED
  • No physical disabilities preventing study participation
  • Willingness to complete all study-related activities for 12 weeks
Not Eligible

You will not qualify if you...

  • Diagnosis of mild cognitive impairment or dementia
  • History of neurological events affecting cognition
  • Presence of severe psychiatric disorders (mild depressive or anxiety symptoms allowed)
  • Inability to travel to the session site (online option available for REMINDER group)
  • Illiteracy

AI-Screening

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Trial Site Locations

Total: 1 location

1

Faculty of Psychology and Educational Sciences

Coimbra, Portugal, 3002-115

Actively Recruiting

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Research Team

A

Ana Rita Silva, PhD

CONTACT

U

University of Coimbra

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

3

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