Actively Recruiting
Clinical, Laboratory and Ultrasound Stratification of Patients With Juvenile Idiopathic Arthritis and Outcomes Evaluation During Transition to Adult Care
Led by IRCCS Burlo Garofolo · Updated on 2024-06-14
80
Participants Needed
2
Research Sites
78 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Juvenile Idiopathic Arthritis (JIA) is the most common chronic rheumatologic disease in children, defined by arthritis lasting at least six weeks without a known cause in patients under 16. This condition includes various diseases grouped under the current classification system, which may not accurately reflect the differences in disease types or severity. Researchers aim to improve classification using clinical, laboratory, and ultrasound data to personalize treatment and better understand disease biology, especially during transition from pediatric to adult care. This observational study follows patients with new or ongoing JIA to evaluate disease activity and joint damage as they transition to adult care. The study uses tools like musculoskeletal ultrasound to detect inflammation and patterns of joint involvement, which may guide treatment choices. Patients are grouped based on disease onset or follow-up status, and assessments include clinical and imaging evaluations. Participants will be monitored between ages 14 and 17, with evaluations including the Juvenile Arthritis Disease Activity Score, Health Assessment Questionnaire - Disability Index, and radiological exams to assess joint damage. The study also measures non-inflammatory pain using a widespread pain index scale. The goal is to track disease progression and outcomes during this critical transition period, providing detailed patient data over time to support personalized care strategies.
CONDITIONS
Brief Title
Clinical, Laboratory and Ultrasound Stratification of Patients With Juvenile Idiopathic Arthritis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects under the age of 18 years
- Arthritis persisting for at least 6 weeks with no known cause
You will not qualify if you...
- No consent from the patients' guardians
- Patients with Systemic onset Juvenile Idiopathic Arthritis
- Patients who developed arthritis on a pre-existing inflammatory disorder such as Inflammatory Bowel Disease, and had received previous treatments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Between 14 and 17 years of age
Participants are observed to evaluate disease activity, joint damage, and pain during the transition to adult care.
Periodic visits during the transition period
Trial Site Locations
Total: 2 locations
1
IRCCS Burlo Garofolo
Trieste, Italy, 34137
Actively Recruiting
2
(Department of Medical and Biological Sciences, Rheumatology Clinic, University of Udine
Udine, Italy
Actively Recruiting
Research Team
S
Serena Pastore, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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