Actively Recruiting
A Clinical Study Evaluating the Efficacy of an Interdental Brush Versus Comparators in Adults With Periodontal Disease
Led by Pierre Fabre Dermo Cosmetique · Updated on 2026-05-08
88
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to evaluate how well a tested interdental brush works compared to other interdental brushes in adults with periodontal disease. The study focuses on adults aged 18 to 80 years who have active generalized periodontal disease. It is a randomized, split-mouth study conducted at a single center lasting about 4 weeks. Participants will use the tested interdental brush on one side of their mouth and a comparative interdental brush on the opposite side. Both brushes are used twice a day for the full 4 weeks. The study includes three visits: a pre-inclusion visit for information and eligibility check, an inclusion visit for randomization and start of brush use, and an end-of-study visit roughly one month later. During the study, researchers will measure changes in dental plaque, gingival bleeding, and pocket depth from the start to the end of the study. Participants will also assess their interdental hygiene and complete a questionnaire on acceptability of the brushes. Adverse events will be recorded throughout. The total study duration for participants is about one month with close monitoring.
CONDITIONS
Brief Title
Comparison Between Different Interdental Brushes in Adults With Periodontal Disease.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged between 18 and 80 years
- Provided written informed consent to participate
- Diagnosed with active generalized periodontal disease (excluding gingivitis)
- Have at least 20 natural teeth, with 10 teeth on each side of the mouth
You will not qualify if you...
- Unable to understand study information or provide written consent due to language or psychiatric reasons
- Pregnant, breastfeeding, or planning pregnancy during the study (for women of childbearing potential)
- Have other oral conditions besides periodontal disease or orthodontic issues that interfere with assessments
- Currently using or planning to use systemic or topical treatments in the mouth that could affect study results
- Received periodontal therapy like scaling, root planing, or surgery within 2 months before inclusion
- Underwent or planned oral or gum surgery within 2 months before inclusion or during the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - Up to 3 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) during the pre-inclusion period
Duration - 4 weeks
Participants use two different interdental brushes on each side of the mouth twice a day to compare their efficacy.
1 baseline visit and 1 follow-up visit
Trial Site Locations
Total: 1 location
1
Cliniques universitaires Saint-Luc
Brussels, Belgium, 1200
Actively Recruiting
Research Team
A
Adeline BACQUEY
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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