Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
ID07574827

Prevalence and Impact of Candida Albicans in Syrian Patients With Periodontitis: A Cross-Sectional Study

Led by Al-Hawash Private University · Updated on 2026-05-08

100

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating the role of Candida albicans, a common fungal pathogen, in patients with periodontitis, an oral disease characterized by inflammation and destruction of the structures supporting the teeth. This study focuses on Syrian patients to better understand how Candida albicans may affect periodontal health in this population. The study is observational and aims to identify the presence and impact of this fungus in people with chronic periodontitis. Participants will undergo a clinical periodontal assessment, including examination of attachment loss and probing depth. Samples of plaque from beneath the gums (subgingival pockets) will be collected for microbiological testing to detect Candida albicans. The study groups include Syrian patients diagnosed with periodontitis and Syrian individuals without periodontal disease. During the study, participants will be assessed at enrollment with periodontal screening and recording index measurements. Researchers will analyze subgingival samples to detect Candida species. The study involves no treatment and aims to monitor oral health status and fungal presence. Participation requires consent and includes patients aged 18 years and older. The study is expected to continue until September 2026.

CONDITIONS

Brief Title

Candida Albicans in Syrian Patients With Periodontitis

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 years and older
  • Diagnosed with chronic periodontitis based on clinical examination
  • Consent to participate in the study
Not Eligible

You will not qualify if you...

  • Patients with systemic diseases affecting oral health such as diabetes or immunosuppressive conditions
  • Recent antibiotic or antifungal treatment within the last three months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - At enrollment

Participants undergo periodontal assessment and collection of subgingival plaque samples to detect Candida Albicans and assess periodontal status.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

Al-Hawash Private University, Faculty of Dentistry

Homs, Syria

Actively Recruiting

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Research Team

A

Ali Abou Sulaiman

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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