Actively Recruiting

Phase Not Applicable
Age: 60Years +
All Genders
ID06358404

Developing a Peer Support Intervention for Depression in Subjective Cognitive Decline

Led by Massachusetts General Hospital · Updated on 2025-05-12

30

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

M

Massachusetts General Hospital

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating an 8-week peer support intervention called PeersCOG for adults aged 60 and older who have depression and subjective cognitive decline. This study aims to assess how feasible, acceptable, and faithfully the peer coaching can be delivered to help manage depression in this population. The study is open-label and involves community-dwelling older adults. The intervention involves trained and supervised peer coaches providing emotional, appraisal, and informational support through weekly video chats. The peer coaches will interact with participants over 8 weeks using video and text messages. Participants may also name a study partner to support them throughout the study, though this is not required. The study will use mixed methods to evaluate the intervention. Participants will have assessments at baseline, 8 weeks, and 3 months to measure depression, subjective cognitive decline, functioning, and social factors using validated tools. Post-intervention interviews with stakeholders will take place at 8 weeks. The study monitors feasibility, acceptability, and fidelity during the intervention period. Participation includes regular contact and questionnaires over about three months.

CONDITIONS

Brief Title

Developing a Peer Support Intervention for Depression in SCD

Who Can Participate

Age: 60Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 60 years or older
  • Endorse subjective cognitive decline
  • Endorse depressive symptoms
  • Not currently experiencing suicidal ideation nor active, untreated manic, psychotic, or substance use disorder
  • Fluent in English and able to give informed consent
Not Eligible

You will not qualify if you...

  • Meets diagnostic criteria for mild cognitive impairment or Alzheimer's dementia
  • Meets diagnostic criteria for a current major depressive disorder
  • History of neurological and psychiatric comorbidities such as major depressive disorder in the past 12 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Outpatient Treatment

Duration - 8 weeks

Participants engage in an 8-week intervention involving weekly video chats with trained peer coaches providing emotional, appraisal, and informational support for depression and subjective cognitive decline.

Weekly video chats

Follow-up

Duration - Approximately 4 weeks

Participants are assessed at 3 months after the intervention to evaluate outcomes related to depression, subjective cognitive decline, functioning, and social factors.

1 follow-up visit (remote or in-person)

Trial Site Locations

Total: 1 location

1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114

Actively Recruiting

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Research Team

J

Jin Hui Joo, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

HEALTH_SERVICES_RESEARCH

Number of Arms

1

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