Actively Recruiting

Phase Not Applicable
Age: 21Years - 50Years
All Genders
Healthy Volunteers
NCT06259916

Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)

Led by Colorado State University · Updated on 2025-11-13

99

Participants Needed

1

Research Sites

125 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a randomized, parallel-group study designed to explore the differences between cannabis intoxication, alcohol intoxication and co-intoxication involving both alcohol and cannabis, utilizing electroencephalography (EEG) as well as more traditional intoxication measures such as breath alcohol concentration and balance metrics. If eligible for the study, participants will be randomized to complete one study session in our mobile laboratory, during which they will use either alcohol, cannabis (which will be self-administered, ad libitum) or both alcohol and cannabis.

CONDITIONS

Official Title

Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)

Who Can Participate

Age: 21Years - 50Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 21 and 50 years
  • Heavy alcohol drinkers (more than 4 drinks/day or 14 drinks/week for men; more than 3 drinks/day or 7 drinks/week for women)
  • Regular users of legal-market flower cannabis at least twice a week in the past 3 months
  • Report using alcohol and legal-market flower cannabis together at least once per month in the past 3 months
  • Able to speak English
Not Eligible

You will not qualify if you...

  • Daily tobacco users
  • Diagnosed with or seeking treatment for alcohol use disorder or other substance use disorders
  • Females who are pregnant, breastfeeding, or trying to become pregnant
  • History or current diagnosis of psychotic, bipolar, or major depressive disorder with suicidal thoughts
  • Current use of psychotropic medications except antidepressants
  • Illicit drug use in the past 60 days or positive drug screen on study day
  • Major medical conditions that contraindicate alcohol or cannabis use

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Colorado State University

Fort Collins, Colorado, United States, 80523

Actively Recruiting

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Research Team

H

Hollis C Karoly, PhD

CONTACT

P

Patricia Davies, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

3

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