Actively Recruiting
Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries
Led by Rawalpindi Medical College · Updated on 2025-07-30
70
Participants Needed
1
Research Sites
13 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient. Lung protective ventilation provides breathing at a set volume determined by patient ideal body weight, along with a set rate to maintain adequate breathing. The pressures in the lower airway are kept less than 30 cm of H20 while a pressure of 5cm of H20 is applied to prevent lung collapse. Recently to above mentioned regimen a driving pressure is added which is a difference between lower airway pressure and pressure applied to prevent lung collapse. Ventilatory settings are adjusted to keep this driving pressure less than 15 cm of H2O.
CONDITIONS
Official Title
Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries
Who Can Participate
Eligibility Criteria
You may qualify if you...
- American Society of Anesthesiologists (ASA) class I and II
- Elective laparoscopic surgeries requiring general anesthesia and mechanical ventilation
- Patients receiving neuromuscular blockade during surgery
- Mechanical ventilation for at least 1 hour during surgery
You will not qualify if you...
- Pregnant patients
- Mechanical ventilation for more than 1 hour in the previous 2 weeks
- Body mass index greater than 35 kg/m2
- Smokers and patients classified as ASA class III or above
- Undergoing thoracic or cardiac surgery
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Benazir Bhutto Hospital
Rawalpindi, Punjab Province, Pakistan, 46000
Actively Recruiting
Research Team
H
Huda Tariq, MBBS
CONTACT
A
Abeera Zareen, MBBS,FCPS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here