Effects of fresh mango consumption on cardiometabolic risk factors in overweight and obese adults.
Martin Rosas, Sherry Pinneo, Celeste O'Mealy...
https://pubmed.ncbi.nlm.nih.gov/34953634/Actively Recruiting
Led by San Diego State University · Updated on 2026-01-21
50
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying the effects of eating fresh mango pulp on feelings of fullness and metabolic health in adults who are overweight or obese. The study aims to understand how mango consumption influences satiety and changes in blood sugar and insulin levels over time. Participants are randomly assigned to one of two groups for 12 weeks. One group consumes 100 calories of low fat cookies daily, while the other group consumes 100 calories of fresh mango fruit daily. The study compares these two snack interventions to evaluate their effects on metabolic parameters. During the study, participants will have their satiety levels measured at multiple times after eating the snack, along with blood tests to monitor glucose and insulin at the start and at week 12. Additional assessments include changes in the gut microbiome at baseline, week 4, and week 12. The study is conducted without masking and is sponsored by San Diego State University.
CONDITIONS
Effects of Fresh Mango Pulp Consumption on Satiety and Cardiometabolic Health
M
Mee Young Hong
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San Diego State University
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Fresh Mango Pulp | Low Fat Cookie |
|---|---|---|
| What it is | Fresh mango pulp, studied as a snack option to assess its impact on satiety and metabolic health in overweight or obese adults. | Low fat cookies, served as an alternative snack to evaluate effects on satiety and metabolic parameters. |
| Role in trial | Participants consume fresh mango pulp during one assigned condition. Outcomes are measured following snack consumption. | Participants consume low fat cookies during a separate assigned condition. Outcomes are measured following snack consumption. |
| Primary use/purpose | To evaluate whether fresh mango pulp leads to greater satiety and improved glucose and insulin responses compared to cookies. | To serve as a comparator snack for measuring satiety and metabolic response relative to mango pulp. |
| How it is given/performed | Participants consume a prepared portion of fresh mango pulp as a snack during the study visits. Outcomes are tracked over two hours after snack intake. | Participants consume a portion of low fat cookies as a snack during the study visits, followed by outcome tracking over two hours. |
| Evidence status | Published studies show mango consumption leads to greater satiety and improved postprandial glucose and insulin responses compared to cookies in overweight and obese adults. | Serves as a comparator. Less satiety effect and less favorable metabolic response were observed compared to mango pulp. |
| Important limitations | Small sample size, short-term snack exposure, and the crossover design limit long-term generalizations regarding mango's effect on metabolic health. Study population included only overweight/obese adults ages 18-55. | Short-term observation following cookie consumption limits broader dietary recommendations. Study findings apply only to overweight/obese adults ages 18-55 within study protocol. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks per intervention period
Participants consume either 100 kcal of low fat cookies or 100 kcal of mango fruit daily to study effects on satiety and cardiometabolic health.
Visits at baseline, week 4, and week 12 for assessments
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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Martin Rosas, Sherry Pinneo, Celeste O'Mealy...
https://pubmed.ncbi.nlm.nih.gov/34953634/Sherry Pinneo, Celeste O'Mealy, Martin Rosas...
https://pubmed.ncbi.nlm.nih.gov/34813369/San Diego State University
Lead Sponsor