Effects of Fresh Watermelon Consumption on the Acute Satiety Response and Cardiometabolic Risk Factors in Overweight and Obese Adults.
Tiffany Lum, Megan Connolly, Amanda Marx...
https://pubmed.ncbi.nlm.nih.gov/30870970/Actively Recruiting
Led by San Diego State University · Updated on 2026-01-21
40
Participants Needed
1
Research Sites
2 weeks
Total Duration
Researchers are investigating how eating fresh watermelon fruit affects feelings of fullness, metabolic health, and weight control. The study focuses on adults between 18 and 55 years old with a body mass index BMI between 25 and 40. The research aims to explore the potential impacts of watermelon consumption on satiety and cardiometabolic health. Participants will be divided into two groups one group will consume 100 calories of fresh watermelon about 2 cups daily for four weeks, while the other group will consume 100 calories of low-fat cookies each day for the same duration. This comparison will help assess differences in satiety and metabolic responses between the two snacks. During the study, researchers will measure changes in participants feelings of fullness at several time points after eating the snack, specifically at 0, 20, 40, 60, 90, and 120 minutes. Participants will be monitored for four weeks, with assessments focused on satiety and metabolic parameters. The study is sponsored by San Diego State University and is designed to include healthy adult volunteers.
CONDITIONS
Effects of Fresh Watermelon Consumption on Satiety and Cardiometabolic Health
M
Mee Young Hong
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San Diego State University
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Daily Fresh Watermelon (2 cups, 100 Kcal) | Daily Low-Fat Cookies (100 Kcal) |
|---|---|---|
| What it is | Participants consume a portion of fresh watermelon equal to 100 Kcal (about 2 cups) daily as a snack for 4 weeks. | Participants consume low-fat cookies equating to 100 Kcal daily as a snack for 4 weeks. |
| Role in the trial | Investigational dietary intervention tested for effects on satiety and metabolic health. | Standard snack comparator to evaluate changes against the watermelon period. |
| Primary use | Assesses whether a daily watermelon snack can improve satiety in overweight adults and impact cardiometabolic parameters. | Serves as an energy-matched alternative snack for comparison of satiety and metabolic impact. |
| How it is given or performed | Participants eat 2 cups of fresh watermelon, totaling 100 Kcal, once per day as a snack for 4 weeks. | Participants eat a portion of low-fat cookies, totaling 100 Kcal, once per day as a snack for 4 weeks. |
| Evidence status | Previous small studies suggest watermelon snacks may enhance satiety and favorably affect some cardiometabolic markers, but evidence in overweight adults is limited and ongoing. | Low-fat cookies serve as a caloric control. No clinical benefit for satiety or cardiometabolic health established beyond energy content. |
| Important limitations | Evidence is based on small, short-term studies. Results may not reflect long-term health effects or apply to other populations. | Does not provide nutritional benefits beyond calorie content; not intended for long-term dietary improvement. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 4 weeks per treatment period
Participants consume 100 Kcal of watermelon fruit (2 cups) daily for 4 weeks and 100 Kcal of low fat cookies daily for 4 weeks in a crossover design.
Daily consumption during each 4-week period
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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Tiffany Lum, Megan Connolly, Amanda Marx...
https://pubmed.ncbi.nlm.nih.gov/30870970/San Diego State University
Lead Sponsor