Effects of fresh vs dried mango consumption on satiety and postprandial glucose in healthy adults.
Candice Stamper, Sama Safadi, Andrew Gehr...
https://pubmed.ncbi.nlm.nih.gov/37520177/Actively Recruiting
Led by San Diego State University · Updated on 2026-01-21
160
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying how different types of snacks affect feelings of fullness satiety, blood sugar glucose, insulin levels, antioxidant capacity, and anxiety in healthy adults aged 18 to 55 years. The study aims to understand how snack choices influence these responses after eating. Participants are randomly assigned to consume one of several snack types, including pretzels, Brazil nuts, potato chips, mixed nuts, white bread, dried mango, or fresh mango. Each snack is tested to observe the bodys responses shortly after eating. During the study, researchers measure changes in satiety, glucose, insulin, anxiety, and antioxidant levels at various times up to two hours after snack consumption. These measurements help assess the immediate impact of each snack type on the participants metabolism and feelings. The study allows healthy volunteers to participate and monitors their responses carefully.
CONDITIONS
Effects of Snack Types on Acute Glucose and Insulin Response
M
Mee Young Hong
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
San Diego State University
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | Brazil nuts | Mixed nuts | Pretzels | Potato chips | White bread | Mixed nuts (common choice) |
|---|---|---|---|---|---|---|
| What it is | Whole Brazil nuts consumed as one of the experimental snack conditions in a randomized crossover design | A mixed‑nut snack option included among investigational conditions in the trial | Pretzels tested as an active comparator snack condition in the study | Potato chips tested as an active comparator snack condition in the study | White bread tested as an active comparator snack condition in the study | Mixed‑nut snacks are a commonly consumed option and reflect a realistic snack alternative |
| Role in trial | Investigational snack condition | Investigational snack condition | Active comparator snack condition | Active comparator snack condition | Active comparator snack condition | Common current snack option supported by external evidence |
| Primary use | Consumed to assess effects on satiety and post‑meal glucose, insulin, antioxidant capacity, and anxiety | Consumed to assess effects on satiety and post‑meal glucose, insulin, antioxidant capacity, and anxiety | Consumed to compare effects on satiety and post‑meal responses against investigational snacks | Consumed to compare effects on satiety and post‑meal responses against investigational snacks | Consumed to compare effects on satiety and post‑meal responses against investigational snacks | Used generally to support favorable post‑meal metabolic and satiety effects compared to less nutritious snacks |
| How it is given or performed | Participants eat Brazil nuts as a snack under controlled fasting/post‑meal conditions | Participants eat mixed nuts under the same controlled snack conditions | Participants consume pretzels as the active comparator snack | Participants eat potato chips as an active comparator snack | Participants consume white bread as an active comparator snack | Typically consumed as a snack choice aligned with mixed nut studies |
| Evidence status | Investigated but external evidence on satiety or glucose response specifically for Brazil nuts exists | Investigational; external studies show mixed nuts improve satiety and stabilize glucose and insulin versus potato chips | Active comparator in trial; generally higher glycemic snack, external evidence limited | Active comparator in trial; external evidence shows potato chips increased glucose and insulin versus mixed nuts | Active comparator in trial; external evidence on glucose response to white bread higher glycemic index but not directly studied here | External evidence supports improved satiety and stabilized glucose and insulin with mixed nuts compared to less nutritious snacks |
| Important risks | Possible allergy risk in individuals with nut or gluten allergy | Possible allergy risk in individuals with nut or gluten allergy | Possible gluten allergy risk | Possible gluten risk and snack excess calories concerns | Possible gluten allergy risk | Possible nut allergy risk |
| Important limitations | Single‑snack exposure; long‑term effects not established | Single‑snack exposure; trial examines acute effects, not habitual intake | Only acute metabolic responses assessed; real‑world snacking patterns may differ | Short‑term assessment under controlled conditions; habitual effects unknown | Acute response only; dietary context may influence results | External study compares mixed nuts to chips but not to other snack types like pretzels or bread |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
You will not qualify if you...
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Short-term periods on multiple occasions as per crossover design
Participants consume different types of snacks including pretzels, Brazil nuts, potato chips, mixed nuts, white bread, dried mango, and fresh mango to examine postprandial responses such as glucose, insulin, satiety, anxiety, and antioxidant levels.
Multiple visits corresponding to each snack consumption and assessment
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
7
Have more questions? Get in touch with our team for quick support
Candice Stamper, Sama Safadi, Andrew Gehr...
https://pubmed.ncbi.nlm.nih.gov/37520177/San Diego State University
Lead Sponsor