Effects of mixed nut consumption on LDL cholesterol, lipoprotein(a), and other cardiometabolic risk factors in overweight and obese adults.
Chelsea L Nora, Liyue Zhang, Robert J Castro...
https://pubmed.ncbi.nlm.nih.gov/37263914Actively Recruiting
Phase Not Applicable
Age: 18Years - 55Years
All Genders
Healthy Volunteers
ID03375866
Effects of Mixed Nut Consumption on Satiety and Weight Management
Led by San Diego State University · Updated on 2026-01-21
56
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating how eating mixed nuts affects feelings of fullness and weight management in adults. This study aims to understand both the immediate and long-term effects of consuming various nuts like almonds, hazelnuts, pecans, pistachios, walnuts, and peanuts on metabolism and body weight. The study also explores the biological mechanisms behind how nuts may influence food intake and weight loss. Participants are randomly assigned to one of two groups for 16 weeks: one group consumes 240 calories of mixed nuts daily, while the other group consumes 240 calories of pretzels daily. This comparison helps researchers study the effects of nuts against a carbohydrate snack on metabolic health and satiety. During the study, participants have their feelings of fullness measured at multiple times after snack consumption, along with blood tests to check glucose, insulin, cholesterol, and Lp(a) levels at baseline, 40 minutes post snack, and after 8 and 16 weeks of daily intake. Researchers also analyze changes in gut microbiome over the 8 and 16 week periods. The overall study duration and monitoring ensure detailed understanding of how mixed nuts impact weight and metabolic health.
CONDITIONS
Brief Title
Effects of Mixed Nut Consumption on Satiety and Weight Management
Who Can Participate
Age: 18Years - 55Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 55 years
- Body mass index (BMI) between 27 and 40
You will not qualify if you...
- Current smoker
- Pregnant woman
- Required use of dietary supplements
- Required medication for metabolic disorders
- Allergy to nuts or gluten
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Treatment
Duration - 16 weeks
Participants consume 240 kcal of either mixed nuts or pretzels daily as part of the study.
Visits at baseline, 8 weeks, and 16 weeks
Trial Site Locations
Total: 1 location
1
School of Exercise and Nutritional Sciences, SDSU
San Diego, California, United States, 92182-7251
Actively Recruiting
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Research Team
M
Mee Young Hong
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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Published Research Related To This Trial
Effects of Mixed Nut Consumption on Blood Glucose, Insulin, Satiety, and the Microbiome in a Healthy Population: A Pilot Study.
Martin Rosas, Changqi Liu, Mee Young Hong
https://pubmed.ncbi.nlm.nih.gov/37083461