Actively Recruiting

Age: 4Weeks - 18Years
All Genders
NCT06529575

Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children

Led by University of Pennsylvania · Updated on 2025-09-12

650

Participants Needed

3

Research Sites

224 weeks

Total Duration

On this page

Sponsors

U

University of Pennsylvania

Lead Sponsor

C

Children's Hospital of Philadelphia

Collaborating Sponsor

AI-Summary

What this Trial Is About

This multisite study seeks to understand whether and how pulse oximeter accuracy varies across children with different skin colors in real world clinical settings. Many factors can affect how well pulse oximeters work; for example, movement and even fingernail polish. Some studies in adults show that skin color may also affect the pulse oximeter reading. In this study, we will explore pulse oximeter accuracy in children of all skin colors who are undergoing cardiac catheterizations. The study will address limitations of prior work by objectively measuring skin color across multiple dimensions of color and comparing the the pulse oximeter reading to the "gold standard" blood sample measurement.

CONDITIONS

Official Title

Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children

Who Can Participate

Age: 4Weeks - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Child is between 1 month and 18 years old
  • Child is undergoing a cardiac catheterization procedure that typically involves direct arterial oxygen saturation measurement by co-oximeter from a location reflective of systemic saturation.
Not Eligible

You will not qualify if you...

  • Child previously participated in the study
  • Child has differential cyanosis across extremities
  • Child is receiving an intravenous vasoconstrictor prior to procedure
  • Child has a ventricular assist device (VAD)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 3 locations

1

Columbia University Medical Center

New York, New York, United States, 10032

Not Yet Recruiting

2

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

3

Texas Children's Hospital

Houston, Texas, United States, 77030

Not Yet Recruiting

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Research Team

H

Halley Ruppel, PhD

CONTACT

M

Michelle Dunn

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children | DecenTrialz