Actively Recruiting
Gas6 and Soluble MerTK in Periodontal Diseases
Led by Abant Izzet Baysal University · Updated on 2026-04-16
90
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aimed to investigate gingival crevicular fluid (GCF) and serum soluble MerTK (sMerTK) and Gas6 levels in periodontal health and disease. A total of 90 individuals, 30 patients with stage III grade B periodontitis, 30 with gingivitis and 30 periodontally healthy individuals were included. Whole-mouth and site-specific clinical periodontal parameters including probing depth, clinical attachment level, bleeding on probing, gingival index, plaque index were recorded. GCF and serum sMerTK and Gas6 levels were measured by enzyme-linked immunosorbent assay. Statistical analysis was performed by using non-parametric tests.
CONDITIONS
Official Title
Gas6 and Soluble MerTK in Periodontal Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Individuals without systemic diseases that may affect periodontal tissues such as cardiovascular diseases, atherosclerosis, immune system disorders, rheumatoid arthritis, obesity, cancer, and diabetes
- Individuals who have not used antibiotics within the last 3 months
- Individuals not taking any medications known to affect periodontal tissues
- Individuals without infectious diseases such as HIV, hepatitis B virus (HBV), or tuberculosis
- Individuals with at least 16 natural teeth, excluding third molars
- Individuals aged 18 years and older
You will not qualify if you...
- Pregnant or lactating individuals
- Individuals who have received periodontal treatment within the last 6 months
- Current smokers
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Bolu Abant Izzet Baysal University Faculty of Dentistry
Bolu, Bolu, Turkey (Türkiye), 14030
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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