Study on Effects of Cannabis Use During Wisdom Tooth Removal with IV Sedation

What this Trial Is About

Researchers are studying how recreational marijuana or cannabis use affects people undergoing wisdom tooth removal surgery. The study compares two groups those who use marijuanaTHCcannabis and those who do not. The purpose is to observe differences during the procedure, including sedation needs and vital signs, to better understand how cannabis use may relate to sedation and analgesia during this type of surgery. Participants will receive sedation through an IV during their wisdom tooth removal. Researchers will monitor how much sedative medicine is needed and track vital signs such as heart rate, blood pressure, breathing rate, oxygen levels, and carbon dioxide levels from the start of surgery to thirty minutes afterward. Users of marijuanaTHCcannabis will provide a hair or fingernail sample to measure cannabis levels, while non-users will provide a urine sample to confirm no cannabis use. Questionnaires about pain and cannabis use will also be completed. Participants will be asked health questions and provide biological samples before surgery. Vital signs and medication doses will be recorded during and shortly after surgery. Researchers will also assess any complications and sedation depth during the procedure. The study will continue until the end of the surgery with follow-up assessments to understand sedation effects. Participation involves monitoring during the surgery and data collection before and after, with the total involvement lasting through the surgical appointment.

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