Actively Recruiting

Age: 18Years - 75Years
All Genders
ID07578545

The Effect of Paravertebral Block, Intertransverse Block, and Erector Spinae Plane Block on Postoperative Opioid Consumption and Pain Scores in Video-assisted Thoracic Surgery: a Prospective Observational Study

Led by Antalya Training and Research Hospital · Updated on 2026-05-11

96

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of different ultrasound-guided regional anesthesia techniques on postoperative opioid use and pain levels in patients undergoing video-assisted thoracic surgery (VATS). Although VATS is known for faster recovery and less pain compared to traditional thoracotomy, it can still lead to acute and chronic postoperative pain that may affect recovery and increase pulmonary complications. This study aims to compare three specific regional anesthesia methods to improve pain management after VATS. The study compares three groups of patients receiving different ultrasound-guided nerve blocks before surgery: paravertebral block, intertransverse process block, and erector spinae plane block. Each block is performed under standard anesthesia monitoring prior to the surgical procedure. These regional anesthesia techniques are part of a multimodal approach to control pain and reduce opioid consumption after surgery. Participants will undergo the assigned nerve block before VATS and will be monitored for opioid use during the first 24 hours after surgery. Pain scores will be assessed using the Numerical Rating Scale during the same period, and chronic pain presence will be evaluated three months postoperatively. The study tracks opioid consumption and pain levels to understand which block provides better postoperative analgesia while ensuring patient safety and recovery quality.

CONDITIONS

Brief Title

The Impact of Video-assisted Thoracic Surgery and Regional Anaesthesia on Postoperative Opioid Consumption and Pain Scores

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged 18-75 years
  • American Society of Anaesthesiology (ASA) score I-III
  • Body mass index (BMI) less than 35 kg/m2
  • Scheduled for elective video-assisted thoracic surgery (VATS)
Not Eligible

You will not qualify if you...

  • ASA score 4 or higher
  • Body mass index (BMI) 35 kg/m2 or higher
  • Declining to give written informed consent
  • Contraindications for block application
  • Inability to undergo block application
  • History of neurological disease or peripheral nerve disease
  • History of chronic opioid use
  • History of severe liver or kidney failure
  • Patients admitted to intensive care unit postoperatively intubated

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Implementation

Duration - Day of surgery

Participants receive an ultrasound-guided regional anaesthesia block before undergoing video-assisted thoracic surgery (VATS). The blocks include paravertebral, intertransverse process, or erector spinae plane blocks performed under standard anaesthesia monitoring.

1 visit (in-person)

Post-operative Follow-up

Duration - Up to 3 months

Participants are monitored for postoperative opioid consumption and pain scores during the first 24 hours after surgery. Chronic pain is assessed up to 3 months after surgery.

Approximately 2 visits (within 24 hours post-surgery and at 3 months)

Trial Site Locations

Total: 1 location

1

University of Health Sciences, Antalya Training and Research Hospital

Antalya, Muratpaşa, Turkey (Türkiye)

Actively Recruiting

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Research Team

S

Sadik Ozmen

B

Batuhan Kilic

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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Published Research Related To This Trial

Single- versus Multiple-Injection Intertransverse Process Block for VATS: A Randomized Trial on Dermatomal Sensory Blockade.

Kittitorn Supphapipat, Artid Samerchua, Prangmalee Leurcharusmee...

https://pubmed.ncbi.nlm.nih.gov/40978546

A comparison of regional anesthesia techniques in patients undergoing video-assisted thoracic surgery: A network meta-analysis.

Bhushan Sandeep, Xin Huang, Yuan Li...

https://pubmed.ncbi.nlm.nih.gov/36030040