Actively Recruiting
Lactobacillus Reuteri Strain Combination in Children Treated With PPI
Led by University of Bari · Updated on 2024-12-05
172
Participants Needed
1
Research Sites
304 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Probiotics might be of help in preventing dysbiosis and emergence of SIBO. Gastrus consisted of a mixture of two human strains of L. Reuteri DSM 17938 and ATCC PTA 6475; the first have extensive data supporting its use in gastric infections (18) however, it lacks the anti-inflammatory properties that have been provided by L. Reuteri DSM ATCC PTA 6475 that has excellent acid resistance and has strong anti-inflammatory properties (19); for these reasons, Gastrus is the best candidate for this indication.
CONDITIONS
Official Title
Lactobacillus Reuteri Strain Combination in Children Treated With PPI
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Children between 1 month and 14 years old
- Need for proton pump inhibitor therapy for gastroesophageal reflux disease or functional dyspepsia
- Informed consent obtained
You will not qualify if you...
- Neurological disorders such as perinatal cerebral injury or spastic tetraparesis
- Nasogastric feeding
- Known immunodeficiency
- Previous therapy with gastric acid inhibitors
- Helicobacter pylori infection
- Use of prebiotics, probiotics, or symbiotics in the past month
- Malnutrition or severe dystrophy
- Cystic fibrosis
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fernanda
Bari, Italy, 70100
Actively Recruiting
Research Team
R
ruggiero francavilla, professor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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