Actively Recruiting
Bariatric Surgery and Pharmacokinetics of Apixaban: BAR-MEDS Apixaban
Led by Norwegian University of Science and Technology · Updated on 2025-06-06
12
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
N
Norwegian University of Science and Technology
Lead Sponsor
S
St. Olavs Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to understand how bariatric surgery affects the way the body processes the medication apixaban. Changes in stomach acidity, emptying time, and enzyme activity after surgeries like gastric bypass or sleeve gastrectomy may influence how much medicine is absorbed and available in the bloodstream. The study focuses on patients with severe obesity who are preparing for these types of surgeries. Participants will be observed taking their usual prescribed apixaban medication before and after their bariatric surgery. The study will measure apixaban levels in the blood from before surgery up to one year afterward to assess any changes in medication availability caused by the surgical procedures. During the study, participants will have blood tests to measure apixaban concentration over time. Researchers will monitor the medication's presence in the blood to understand how bariatric surgery impacts its absorption and effects. The study lasts up to one year after surgery, with regular follow-up assessments to track these changes.
CONDITIONS
Brief Title
Bariatric Surgery and Pharmacokinetics of Apixaban
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
- Being a Norwegian citizen
- Age between 18 and 70 years
You will not qualify if you...
- Having previously undergone resections in the gastrointestinal tract (GI-tract surgery history)
- Outside the age range of 18 to 70 years
- Not a Norwegian citizen
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Up to 1 year postoperatively
Participants who undergo bariatric surgery are observed to measure apixaban concentration in blood serum up to 1 year after surgery.
Trial Site Locations
Total: 1 location
1
St. Olavs University Hospital
Trondheim, Norway
Actively Recruiting
Research Team
M
Magnus Strømmen, MSc
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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