Study Comparing Thumb and Fifth Finger Muscles for Monitoring Muscle Relaxation During Surgery Using Electromyography

What this Trial Is About

Researchers are evaluating how well the TetraGraph device measures muscle responses at two sites on the arm the adductor pollicis thumb and the abductor digiti minimi fifth digit. The study focuses on the timing of muscle response during the onset and recovery from neuromuscular blockade caused by rocuronium and reversed by sugammadex. This is important because residual muscle weakness after surgery can cause complications, and monitoring this accurately helps improve patient safety. In this observational study, patients undergoing elective surgeries receive neuromuscular blocking agents including rocuronium followed by reversal with sugammadex. Two TetraGraph devices are placed on different muscles to monitor electrical activity through electromyography EMG. Measurements are taken frequently from the start of neuromuscular blockade until recovery, including every 20 seconds after sugammadex administration until the patient is extubated. Participants are monitored continuously during surgery with standard equipment and the TetraGraph devices, with recordings taken every 15 seconds during baseline and every 5 minutes during surgery. After surgery, assessments continue until muscle function recovers to a defined level. Researchers measure the rate of recovery from blockade and the incidence of residual muscle weakness one hour after extubation. The study aims to improve understanding of muscle site sensitivity and monitoring techniques in surgical patients.

Comparison of Adductor Pollicis and Abductor Digiti Minimi Muscles (Thumb Vs. Fifth Digit) As Sites for Neuromuscular Monitoring with Electromyography