Actively Recruiting

Phase Not Applicable
Age: 65Years - 85Years
FEMALE
Healthy Volunteers
ID06670365

Evaluating Heat Acclimation by Warm Water Immersion to Reduce Heat and Cardiovascular Stress in Older Women During Indoor Overheating

Led by University of Ottawa · Updated on 2025-06-15

12

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying ways to help older women become more resilient to heat during indoor overheating events, which are expected to increase due to global warming. The study focuses on women aged 65 to 85, who are more vulnerable to heat stress and related health risks, especially those without access to air conditioning or reliable electricity. Previous findings showed that passive heat exposure like warm-water immersion may improve the body's ability to lose heat and reduce strain, but this has not yet been confirmed in realistic indoor heat conditions for older women. Participants will undergo a 7-day heat acclimation protocol involving warm-water immersion up to shoulder level in approximately 40°C water until their core temperature reaches about 38.5°C and is maintained for 60 minutes. Before and after this protocol, they will be exposed to a 10-hour indoor heat session at 36°C and 45% humidity, simulating extreme indoor heat conditions. During this exposure, participants will mostly remain seated with brief hourly stretching breaks. During the study, researchers will monitor core body temperature, heart rate, blood pressure, cognitive function, balance, and mood among other measures to assess heat and cardiovascular strain. They will also track fluid loss, thirst, thermal comfort, and symptoms related to heat exposure. These evaluations will help determine whether the warm-water immersion protocol reduces the physical and mental stress caused by prolonged heat exposure. The total study duration includes the 7-day immersion period and assessments before and after the heat exposures.

CONDITIONS

Brief Title

Enhancing Heat Resiliency in Older Adults During Indoor Overheating Via Heat Acclimation by Warm Water Immersion

Who Can Participate

Age: 65Years - 85Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Non-smoking
  • Female aged 65 to 85 years
  • Able to speak English or French
  • Able to provide informed consent
  • May have controlled chronic hypertension or type 2 diabetes diagnosed at least 5 years ago
Not Eligible

You will not qualify if you...

  • Severe hypoglycemia episodes or inability to sense hypoglycemia
  • Serious diabetes complications such as gastroparesis, kidney disease, uncontrolled hypertension, severe neuropathy
  • Uncontrolled hypertension (blood pressure >150/95 mmHg sitting)
  • Physical activity restrictions from diseases like unstable cardiac or pulmonary disease, severe arthritis, disabling stroke
  • Use of or recent changes in medication that may affect study participation
  • Cardiac abnormalities found during screening
  • Current smokers or tobacco users (implied from inclusion criteria requiring non-smoking status if applicable)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Daylong Heat Exposure Before Acclimation

Duration - 1 day

Participants undergo a 10-hour passive heat exposure in a climate-controlled chamber set at 36°C and 45% humidity, remaining mostly seated with hourly stretching breaks.

1 visit (in-person)

Heat Acclimation by Warm Water Immersion

Duration - 7 days

Participants are immersed in warm water (~40°C) up to shoulder level until their core temperature reaches 38.5°C for 60 minutes. This warm-water immersion is repeated for 7 consecutive days.

7 visits (in-person, daily)

Daylong Heat Exposure After Acclimation

Duration - 1 day

Participants undergo a second 10-hour passive heat exposure in a climate-controlled chamber set at 36°C and 45% humidity, remaining mostly seated with hourly stretching breaks to assess the effects of acclimation.

1 visit (in-person)

Trial Site Locations

Total: 1 location

1

University of Ottawa

Ottawa, Ontario, Canada, K1N1A2

Actively Recruiting

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Research Team

G

Glen P Kenny, PhD

C

Caroline Li-Maloney, MSc

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

1

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