Actively Recruiting

Phase 4
Age: 18Years +
All Genders
NCT01818661

Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

Led by Mayo Clinic · Updated on 2025-11-12

50

Participants Needed

1

Research Sites

517 weeks

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

N

National Institute on Deafness and Other Communication Disorders (NIDCD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The study is designed to determine the relationship between structural and functional changes in the brain on imaging and progression of speech and language, neurological and neuropsychological features in patients with neurodegenerative apraxia of speech (AOS).

CONDITIONS

Official Title

Longitudinal Multi-Modality Imaging in Progressive Apraxia of Speech

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with neurodegenerative apraxia of speech according to clinical criteria at Mayo Clinic
Not Eligible

You will not qualify if you...

  • Having other illnesses that could explain speech or language problems, such as traumatic brain injury, strokes, or developmental syndromes
  • Pregnant, postpartum, or breastfeeding women
  • Women who can become pregnant must have a pregnancy test within 48 hours before the PET scan
  • Contraindications to MRI such as metal in the head or cardiac pacemaker
  • Severe claustrophobia
  • Conditions that may interfere with brain imaging like structural abnormalities, subdural hematoma, or brain tumors
  • Medically unstable or on medications affecting brain structure or metabolism, such as chemotherapy
  • Lack of an informant or refusal to consent to research participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55905

Actively Recruiting

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Research Team

S

Sarah Boland, CCRP

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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